Hybrid Formulations of Liposomes and Bioadhesive Polymers Improve the Hypotensive Effect of the Melatonin Analogue 5-MCA-NAT in Rabbit Eyes

Daniela Quinteros; Marta Vicario-de-la-Torre; Vanessa Andrés-Guerrero; Santiago Palma; Daniel Allemandi; Rocío Herrero-Vanrell; Irene T. Molina-Martínez

doi:10.1371/journal.pone.0110344

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Peer-reviewed

Research Article

Hybrid Formulations of Liposomes and Bioadhesive Polymers Improve the Hypotensive Effect of the Melatonin Analogue 5-MCA-NAT in Rabbit Eyes

Daniela Quinteros ,

Contributed equally to this work with: Daniela Quinteros, Marta Vicario-de-la-Torre, Vanessa Andrés-Guerrero

Affiliation Department of Pharmacy, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, CONICET, Edificio de Ciencias II, Ciudad Universitaria, Córdoba, Argentina
⨯
Marta Vicario-de-la-Torre ,

Contributed equally to this work with: Daniela Quinteros, Marta Vicario-de-la-Torre, Vanessa Andrés-Guerrero

Affiliation Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Complutense University of Madrid, Pharmaceutical Innovation in Ophthalmology Research Group, Sanitary Research Institute of the San Carlos Clinical Hospital (IdISSC) and the Ocular Pathology National Net (OFTARED) of the Institute of Health Carlos III, Madrid, Spain
⨯
Vanessa Andrés-Guerrero ,

Contributed equally to this work with: Daniela Quinteros, Marta Vicario-de-la-Torre, Vanessa Andrés-Guerrero

Affiliation Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Complutense University of Madrid, Pharmaceutical Innovation in Ophthalmology Research Group, Sanitary Research Institute of the San Carlos Clinical Hospital (IdISSC) and the Ocular Pathology National Net (OFTARED) of the Institute of Health Carlos III, Madrid, Spain
⨯
Santiago Palma,

Affiliation Department of Pharmacy, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, CONICET, Edificio de Ciencias II, Ciudad Universitaria, Córdoba, Argentina
⨯
Daniel Allemandi,

Affiliation Department of Pharmacy, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, CONICET, Edificio de Ciencias II, Ciudad Universitaria, Córdoba, Argentina
⨯
Rocío Herrero-Vanrell,

Affiliation Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Complutense University of Madrid, Pharmaceutical Innovation in Ophthalmology Research Group, Sanitary Research Institute of the San Carlos Clinical Hospital (IdISSC) and the Ocular Pathology National Net (OFTARED) of the Institute of Health Carlos III, Madrid, Spain
⨯
Irene T. Molina-Martínez

* E-mail: iremm@farm.ucm.es

Affiliation Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Complutense University of Madrid, Pharmaceutical Innovation in Ophthalmology Research Group, Sanitary Research Institute of the San Carlos Clinical Hospital (IdISSC) and the Ocular Pathology National Net (OFTARED) of the Institute of Health Carlos III, Madrid, Spain
⨯

Hybrid Formulations of Liposomes and Bioadhesive Polymers Improve the Hypotensive Effect of the Melatonin Analogue 5-MCA-NAT in Rabbit Eyes

Daniela Quinteros,
Marta Vicario-de-la-Torre,
Vanessa Andrés-Guerrero,
Santiago Palma,
Daniel Allemandi,
Rocío Herrero-Vanrell,
Irene T. Molina-Martínez

Published: October 20, 2014
https://doi.org/10.1371/journal.pone.0110344

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