“Glowing Head” Mice: A Genetic Tool Enabling Reliable Preclinical Image-Based Evaluation of Cancers in Immunocompetent Allografts

Chi-Ping Day; John Carter; Zoe Weaver Ohler; Carrie Bonomi; Rajaa El Meskini; Philip Martin; Cari Graff-Cherry; Lionel Feigenbaum; Thomas Tüting; Terry Van Dyke; Melinda Hollingshead; Glenn Merlino

doi:10.1371/journal.pone.0109956

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Open Access

Peer-reviewed

Research Article

“Glowing Head” Mice: A Genetic Tool Enabling Reliable Preclinical Image-Based Evaluation of Cancers in Immunocompetent Allografts

Chi-Ping Day,

Affiliation Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
⨯
John Carter,

Affiliation In Vivo Evaluation, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
⨯
Zoe Weaver Ohler,

Affiliation Center for Advanced Preclinical Research of Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
⨯
Carrie Bonomi,

Affiliation In Vivo Evaluation, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
⨯
Rajaa El Meskini,

Affiliation Center for Advanced Preclinical Research of Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
⨯
Philip Martin,

Affiliation Center for Advanced Preclinical Research of Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
⨯
Cari Graff-Cherry,

Affiliation Laboratory Animal Science Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
⨯
Lionel Feigenbaum,

Affiliation Laboratory Animal Science Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
⨯
Thomas Tüting,

Affiliation Department of Dermatology and Allergy, University Hospital Bonn, Bonn, Germany
⨯
Terry Van Dyke,

Affiliation Center for Advanced Preclinical Research of The Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America
⨯
Melinda Hollingshead,

Affiliation Biological Testing Branch, Developmental Therapeutics Program, National Cancer Institute, Frederick, Maryland, United States of America
⨯
Glenn Merlino

* E-mail: gmerlino@helix.nih.gov

Affiliation Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
⨯

“Glowing Head” Mice: A Genetic Tool Enabling Reliable Preclinical Image-Based Evaluation of Cancers in Immunocompetent Allografts

Chi-Ping Day,
John Carter,
Zoe Weaver Ohler,
Carrie Bonomi,
Rajaa El Meskini,
Philip Martin,
Cari Graff-Cherry,
Lionel Feigenbaum,
Thomas Tüting,
Terry Van Dyke

Published: November 4, 2014
https://doi.org/10.1371/journal.pone.0109956

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03 Sep 2021
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Minor correction Posted by CPD on 03 Sep 2021 at 18:53 GMT
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01 Dec 2016
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FAQ of glowing head mice (2) Posted by CPD on 01 Dec 2016 at 00:12 GMT
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FAQ of glowing head mice Posted by CPD on 22 Oct 2016 at 20:58 GMT

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Lung and intrathoracic tumors
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