Dose Schedule Optimization and the Pharmacokinetic Driver of Neutropenia

Open Access

Peer-reviewed

Research Article

Mayankbhai Patel,

Affiliation Drug Metabolism and Pharmacokinetics, Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America
⨯
Santhosh Palani,

Affiliation Drug Metabolism and Pharmacokinetics, Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America
⨯
Arijit Chakravarty,

Affiliation Drug Metabolism and Pharmacokinetics, Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America
⨯
Johnny Yang,

Affiliation Drug Metabolism and Pharmacokinetics, Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America
⨯
Wen Chyi Shyu,

Affiliation Drug Metabolism and Pharmacokinetics, Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America
⨯
Jerome T. Mettetal

* E-mail: mettetal@alum.mit.edu

Affiliation Drug Metabolism and Pharmacokinetics, Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America
⨯

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Neutropenia
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Dose prediction methods
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Antenatal care
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Neutrophils
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Toxicity
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Drug administration
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Pharmacokinetics
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Simulation and modeling
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