Combination of TRAIL with Bortezomib Shifted Apoptotic Signaling from DR4 to DR5 Death Receptor by Selective Internalization and Degradation of DR4

Open Access

Peer-reviewed

Research Article

Maxim L. Bychkov,

Affiliation Department of Bioengineering, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia
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Marine E. Gasparian ,

* E-mail: marine_gasparian@yahoo.com

Affiliation Department of Bioengineering, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia
⨯
Dmitry A. Dolgikh,

Affiliation Department of Bioengineering, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia
⨯
Mikhail P. Kirpichnikov

Affiliation Department of Bioengineering, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia
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Apoptosis
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Cell death
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Lysosomes
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Cancer treatment
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Drug therapy
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B cell receptors
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Non-small cell lung cancer
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