TGFβ-Induced Deptor Suppression Recruits mTORC1 and Not mTORC2 to Enhance Collagen I (α2) Gene Expression

Falguni Das; Amit Bera; Nandini Ghosh-Choudhury; Hanna E. Abboud; Balakuntalam S. Kasinath; Goutam Ghosh Choudhury

doi:10.1371/journal.pone.0109608

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Peer-reviewed

Research Article

TGFβ-Induced Deptor Suppression Recruits mTORC1 and Not mTORC2 to Enhance Collagen I (α2) Gene Expression

Falguni Das,

Affiliation Departments of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
⨯
Amit Bera,

Affiliation Departments of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
⨯
Nandini Ghosh-Choudhury,

Affiliations Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, VA Research, South Texas Veterans Health Care System, San Antonio, Texas, United States of America
⨯
Hanna E. Abboud,

Affiliations Departments of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, VA Research, South Texas Veterans Health Care System, San Antonio, Texas, United States of America
⨯
Balakuntalam S. Kasinath,

Affiliations Departments of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, VA Research, South Texas Veterans Health Care System, San Antonio, Texas, United States of America
⨯
Goutam Ghosh Choudhury

* E-mail: choudhuryg@uthscsa.edu

Affiliations Departments of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, Geriatric Research, Education and Clinical Center, South Texas Veterans Health Care System, San Antonio, Texas, United States of America, VA Research, South Texas Veterans Health Care System, San Antonio, Texas, United States of America
⨯

TGFβ-Induced Deptor Suppression Recruits mTORC1 and Not mTORC2 to Enhance Collagen I (α2) Gene Expression

Falguni Das,
Amit Bera,
Nandini Ghosh-Choudhury,
Hanna E. Abboud,
Balakuntalam S. Kasinath,
Goutam Ghosh Choudhury

Published: October 15, 2014
https://doi.org/10.1371/journal.pone.0109608

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Epithelial cells
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Transfection
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Gene expression
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