Enhanced Cytotoxicity of Natural Killer Cells following the Acquisition of Chimeric Antigen Receptors through Trogocytosis

Fu-Nan Cho; Tsung-Hsien Chang; Chih-Wen Shu; Ming-Chin Ko; Shuen-Kuei Liao; Kang-Hsi Wu; Ming-Sun Yu; Shyh-Jer Lin; Ying-Chung Hong; Chien-Hsun Chen; Chien-Hui Hung; Yu-Hsiang Chang

doi:10.1371/journal.pone.0109352

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Open Access

Peer-reviewed

Research Article

Enhanced Cytotoxicity of Natural Killer Cells following the Acquisition of Chimeric Antigen Receptors through Trogocytosis

Fu-Nan Cho ,

Contributed equally to this work with: Fu-Nan Cho, Tsung-Hsien Chang

Affiliation Department of Obstetrics and Gynecology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
⨯
Tsung-Hsien Chang ,

Contributed equally to this work with: Fu-Nan Cho, Tsung-Hsien Chang

Affiliation Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
⨯
Chih-Wen Shu,

Affiliation Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
⨯
Ming-Chin Ko,

Affiliation Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
⨯
Shuen-Kuei Liao,

Affiliation Graduate Institute of Cancer Biology and Drug Discovery and Center of Excellence for Cancer Research, Taipei Medical University, Taipei, Taiwan
⨯
Kang-Hsi Wu,

Affiliation Department of Pediatrics, Children's Hospital and School of Chinese Medicine, China Medical University Hospitals, Taichung, Taiwan
⨯
Ming-Sun Yu,

Affiliation Haematology-Oncology Section, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
⨯
Shyh-Jer Lin,

Affiliation Haematology-Oncology Section, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
⨯
Ying-Chung Hong,

Affiliation Haematology-Oncology Section, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
⨯
Chien-Hsun Chen,

Affiliation Department of Radiation Oncology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
⨯
Chien-Hui Hung,

Affiliation Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
⨯
Yu-Hsiang Chang

* E-mail: yhchang@vghks.gov.tw

Affiliations Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan, Department of Nursing, Tajen University, Yanpu Township, Pingtung County, Taiwan
⨯

Enhanced Cytotoxicity of Natural Killer Cells following the Acquisition of Chimeric Antigen Receptors through Trogocytosis

Fu-Nan Cho,
Tsung-Hsien Chang,
Chih-Wen Shu,
Ming-Chin Ko,
Shuen-Kuei Liao,
Kang-Hsi Wu,
Ming-Sun Yu,
Shyh-Jer Lin,
Ying-Chung Hong,
Chien-Hsun Chen

Published: October 14, 2014
https://doi.org/10.1371/journal.pone.0109352

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