Sequential Application of Ligand and Structure Based Modeling Approaches to Index Chemicals for Their hH₄R Antagonism

• Matteo Pappalardo ,

  Contributed equally to this work with: Matteo Pappalardo, Nir Shachaf

  Affiliation Department of Chemical Sciences, University of Catania, Catania, Italy

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• Nir Shachaf ,

  Contributed equally to this work with: Matteo Pappalardo, Nir Shachaf

  Affiliation Drug Discovery Informatics Lab, QRC-Qasemi Research Center, Al-Qasemi Academic College, Baka El-Garbiah, Israel

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• Livia Basile,

  Affiliation Etnalead s.r.l., Scuola Superiore di Catania, University of Catania, Catania, Italy

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• Danilo Milardi,

  Affiliation National Research Council, Institute of Biostructures and Bioimaging, Catania, Italy

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• Mouhammed Zeidan,

  Affiliation Drug Discovery Informatics Lab, QRC-Qasemi Research Center, Al-Qasemi Academic College, Baka El-Garbiah, Israel

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• Jamal Raiyn,

  Affiliation Drug Discovery Informatics Lab, QRC-Qasemi Research Center, Al-Qasemi Academic College, Baka El-Garbiah, Israel

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• Salvatore Guccione ,

  * E-mail: guccione@unict.it (SG); a_rayan@qsm.ac.il (AR)

  Affiliations Etnalead s.r.l., Scuola Superiore di Catania, University of Catania, Catania, Italy, Department of Pharmaceutical Sciences, University of Catania, Catania, Italy

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• Anwar Rayan

  * E-mail: guccione@unict.it (SG); a_rayan@qsm.ac.il (AR)

  Affiliation Drug Discovery Informatics Lab, QRC-Qasemi Research Center, Al-Qasemi Academic College, Baka El-Garbiah, Israel

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