A Dynamic View of Molecular Switch Behavior at Serotonin Receptors: Implications for Functional Selectivity

Open Access

Peer-reviewed

Research Article

Maria Martí-Solano,

Affiliation Research Programme on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences, Universitat Pompeu Fabra, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain
⨯
Ferran Sanz,

Affiliation Research Programme on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences, Universitat Pompeu Fabra, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain
⨯
Manuel Pastor ,

* E-mail: manuel.pastor@upf.edu (MP); jana.selent@upf.edu (JS)

Affiliation Research Programme on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences, Universitat Pompeu Fabra, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain
⨯
Jana Selent

* E-mail: manuel.pastor@upf.edu (MP); jana.selent@upf.edu (JS)

Affiliation Research Programme on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences, Universitat Pompeu Fabra, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain
⨯

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Serotonin
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Serotonin receptors
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Crystal structure
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Intracellular receptors
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Molecular dynamics
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G protein coupled receptors
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Distance measurement
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Biochemical simulations
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