Evaluation of the Highly Variable Agomelatine Pharmacokinetics in Chinese Healthy Subjects to Support Bioequivalence Study

• Qi Pei ,

  Contributed equally to this work with: Qi Pei, Yan Wang

  Affiliation Department of pharmacy, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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• Yan Wang ,

  Contributed equally to this work with: Qi Pei, Yan Wang

  Affiliation Department of pharmacy, Changde First People's Hospital, Changde, Hunan, China

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• Zhe-Yi Hu,

  Affiliation Department of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America

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• Shi-Kun Liu,

  Affiliation Department of pharmacy, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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• Hong-Yi Tan,

  Affiliation Center of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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• Cheng-Xian Guo,

  Affiliation Center of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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• Ran-Ran Zhang,

  Affiliation Center of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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• Yu-Xia Xiang,

  Affiliation Center of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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• Jie Huang,

  Affiliation Center of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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• Lu Huang,

  Affiliation Center of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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• Hong Yuan,

  Affiliation Center of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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• Guo-Ping Yang

  * E-mail: ygp9880@126.com

  Affiliation Center of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China

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