Computational Design of Protein-Based Inhibitors of Plasmodium vivax Subtilisin-Like 1 Protease

Giacomo Bastianelli; Anthony Bouillon; Christophe Nguyen; Dung Le-Nguyen; Michael Nilges; Jean-Christophe Barale

doi:10.1371/journal.pone.0109269

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Peer-reviewed

Research Article

Computational Design of Protein-Based Inhibitors of Plasmodium vivax Subtilisin-Like 1 Protease

Giacomo Bastianelli,

Affiliations Institut Pasteur, Unité de Bioinformatique Structurale, Département de Biologie Structurale et Chimie, Paris, France, CNRS UMR 3528, Paris, France
⨯
Anthony Bouillon,

Current address: Institut Pasteur, Unité de Biologie et Génétique du Paludisme, Team Malaria Targets and Drug Development, Département de Parasitologie et de Mycologie, Paris, France

Affiliations Institut Pasteur, Unité d’Immunologie Moléculaires des Parasites, Département de Parasitologie et de Mycologie & CNRS URA 2581, Paris, France, CNRS, URA2581, Paris, France
⨯
Christophe Nguyen,

Affiliation SYSDIAG, CNRS UMR3145 CNRS-BioRad, Montpellier, France
⨯
Dung Le-Nguyen,

Affiliation SYSDIAG, CNRS UMR3145 CNRS-BioRad, Montpellier, France
⨯
Michael Nilges ,

Contributed equally to this work with: Michael Nilges, Jean-Christophe Barale

* E-mail: nilges@pasteur.fr (MN); jcb@pasteur.fr (JCB)

Affiliations Institut Pasteur, Unité de Bioinformatique Structurale, Département de Biologie Structurale et Chimie, Paris, France, CNRS UMR 3528, Paris, France
⨯
Jean-Christophe Barale

Contributed equally to this work with: Michael Nilges, Jean-Christophe Barale

* E-mail: nilges@pasteur.fr (MN); jcb@pasteur.fr (JCB)

Current address: Institut Pasteur, Unité de Biologie et Génétique du Paludisme, Team Malaria Targets and Drug Development, Département de Parasitologie et de Mycologie, Paris, France

Affiliations Institut Pasteur, Unité d’Immunologie Moléculaires des Parasites, Département de Parasitologie et de Mycologie & CNRS URA 2581, Paris, France, CNRS, URA2581, Paris, France
⨯

Computational Design of Protein-Based Inhibitors of Plasmodium vivax Subtilisin-Like 1 Protease

Giacomo Bastianelli,
Anthony Bouillon,
Christophe Nguyen,
Dung Le-Nguyen,
Michael Nilges,
Jean-Christophe Barale

Published: October 24, 2014
https://doi.org/10.1371/journal.pone.0109269

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