Voluntary Exercise Prevents Cisplatin-Induced Muscle Wasting during Chemotherapy in Mice

Pernille Hojman; Jonas Fjelbye; Bo Zerahn; Jesper F. Christensen; Christine Dethlefsen; Camilla K. Lonkvist; Claus Brandt; Hanne Gissel; Bente Klarlund Pedersen; Julie Gehl

doi:10.1371/journal.pone.0109030

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Open Access

Peer-reviewed

Research Article

Voluntary Exercise Prevents Cisplatin-Induced Muscle Wasting during Chemotherapy in Mice

Pernille Hojman ,

* E-mail: phojman@inflammation-metabolism.dk (PH); Julie.Gehl@regionh.dk (JG)

Affiliation The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
⨯
Jonas Fjelbye,

Affiliation The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
⨯
Bo Zerahn,

Affiliation Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital Herlev, Herlev, Denmark
⨯
Jesper F. Christensen,

Affiliation Copenhagen University Hospital, The University Hospitals Centre for Health Care Research (UCSF), Copenhagen, Denmark
⨯
Christine Dethlefsen,

Affiliation The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
⨯
Camilla K. Lonkvist,

Affiliation Department of Oncology, Copenhagen University Hospital Herlev, Herlev, Denmark
⨯
Claus Brandt,

Affiliation The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
⨯
Hanne Gissel ,

¶† Deceased.

Affiliation Institute of Biomedicine, University of Aarhus, Aarhus C, Denmark
⨯
Bente Klarlund Pedersen,

Affiliation The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
⨯
Julie Gehl

* E-mail: phojman@inflammation-metabolism.dk (PH); Julie.Gehl@regionh.dk (JG)

Affiliation Department of Oncology, Copenhagen University Hospital Herlev, Herlev, Denmark
⨯

Voluntary Exercise Prevents Cisplatin-Induced Muscle Wasting during Chemotherapy in Mice

Pernille Hojman,
Jonas Fjelbye,
Bo Zerahn,
Jesper F. Christensen,
Christine Dethlefsen,
Camilla K. Lonkvist,
Claus Brandt,
Hanne Gissel,
Bente Klarlund Pedersen,
Julie Gehl

Published: September 30, 2014
https://doi.org/10.1371/journal.pone.0109030

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