Autonomous Stimulation of Cancer Cell Plasticity by the Human NKG2D Lymphocyte Receptor Coexpressed with Its Ligands on Cancer Cells

Xin Cai; Zhenpeng Dai; Rebecca S. Reeves; Andrea Caballero-Benitez; Kate L. Duran; Jeffrey J. Delrow; Peggy L. Porter; Thomas Spies; Veronika Groh

doi:10.1371/journal.pone.0108942

Loading metrics

Open Access

Peer-reviewed

Research Article

Autonomous Stimulation of Cancer Cell Plasticity by the Human NKG2D Lymphocyte Receptor Coexpressed with Its Ligands on Cancer Cells

Xin Cai,

Affiliation Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Zhenpeng Dai,

Affiliation Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Rebecca S. Reeves,

Affiliation Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Andrea Caballero-Benitez,

Affiliation Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Kate L. Duran,

Affiliation Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Jeffrey J. Delrow,

Affiliation Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Peggy L. Porter,

Affiliation Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Thomas Spies ,

Contributed equally to this work with: Thomas Spies, Veronika Groh

* E-mail: tspies@fhcrc.org

¶These authors are senior authors on this work.

Affiliation Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Veronika Groh

Contributed equally to this work with: Thomas Spies, Veronika Groh

¶These authors are senior authors on this work.

Affiliation Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯

Autonomous Stimulation of Cancer Cell Plasticity by the Human NKG2D Lymphocyte Receptor Coexpressed with Its Ligands on Cancer Cells

Xin Cai,
Zhenpeng Dai,
Rebecca S. Reeves,
Andrea Caballero-Benitez,
Kate L. Duran,
Jeffrey J. Delrow,
Peggy L. Porter,
Thomas Spies,
Veronika Groh

Published: October 7, 2014
https://doi.org/10.1371/journal.pone.0108942

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Prostate cancer
Is the Subject Area "Prostate cancer" applicable to this article?

Thanks for your feedback.
Cloning
Is the Subject Area "Cloning" applicable to this article?

Thanks for your feedback.
Flow cytometry
Is the Subject Area "Flow cytometry" applicable to this article?

Thanks for your feedback.
Immunoblotting
Is the Subject Area "Immunoblotting" applicable to this article?

Thanks for your feedback.
Invasive tumors
Is the Subject Area "Invasive tumors" applicable to this article?

Thanks for your feedback.
Reverse transcriptase-polymerase chain reaction
Is the Subject Area "Reverse transcriptase-polymerase chain reaction" applicable to this article?

Thanks for your feedback.
Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.