Prostate Tumor-Derived Exosomes Down-Regulate NKG2D Expression on Natural Killer Cells and CD8+ T Cells: Mechanism of Immune Evasion

Open Access

Peer-reviewed

Research Article

Prostate Tumor-Derived Exosomes Down-Regulate NKG2D Expression on Natural Killer Cells and CD8⁺ T Cells: Mechanism of Immune Evasion

Marie Lundholm ,

* E-mail: marie.lundholm@medbio.umu.se

Affiliation Department of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden
⨯
Mona Schröder,

Affiliation Department of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden
⨯
Olga Nagaeva,

Affiliation Department of Clinical Microbiology, Clinical Immunology, Umeå University, Umeå, Sweden
⨯
Vladimir Baranov,

Affiliation Department of Clinical Microbiology, Clinical Immunology, Umeå University, Umeå, Sweden
⨯
Anders Widmark,

Affiliation Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden
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Lucia Mincheva-Nilsson,

Affiliation Department of Clinical Microbiology, Clinical Immunology, Umeå University, Umeå, Sweden
⨯
Pernilla Wikström

Affiliation Department of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden
⨯

Exosomes
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Prostate cancer
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T cells
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Cytotoxic T cells
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NK cells
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Flow cytometry
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Lung and intrathoracic tumors
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Lymphocytes
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