Spred-2 Deficiency Exacerbates Lipopolysaccharide-Induced Acute Lung Inflammation in Mice

Yang Xu; Toshihiro Ito; Soichiro Fushimi; Sakuma Takahashi; Junya Itakura; Ryojiro Kimura; Miwa Sato; Megumi Mino; Akihiko Yoshimura; Akihiro Matsukawa

doi:10.1371/journal.pone.0108914

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Open Access

Peer-reviewed

Research Article

Spred-2 Deficiency Exacerbates Lipopolysaccharide-Induced Acute Lung Inflammation in Mice

Yang Xu,

Affiliation Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
⨯
Toshihiro Ito,

Affiliation Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
⨯
Soichiro Fushimi,

Affiliation Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
⨯
Sakuma Takahashi,

Affiliation Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
⨯
Junya Itakura,

Affiliation Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
⨯
Ryojiro Kimura,

Affiliation Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
⨯
Miwa Sato,

Affiliation Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
⨯
Megumi Mino,

Affiliation Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
⨯
Akihiko Yoshimura,

Affiliation Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
⨯
Akihiro Matsukawa

* E-mail: amatsu@md.okayama-u.ac.jp

Affiliation Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
⨯

Spred-2 Deficiency Exacerbates Lipopolysaccharide-Induced Acute Lung Inflammation in Mice

Yang Xu,
Toshihiro Ito,
Soichiro Fushimi,
Sakuma Takahashi,
Junya Itakura,
Ryojiro Kimura,
Miwa Sato,
Megumi Mino,
Akihiko Yoshimura,
Akihiro Matsukawa

Published: October 2, 2014
https://doi.org/10.1371/journal.pone.0108914

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