Integrated mRNA-MicroRNA Profiling of Human NK Cell Differentiation Identifies MiR-583 as a Negative Regulator of IL2Rγ Expression

Sohyun Yun; Su Ui Lee; Jung Min Kim; Hyun-Jun Lee; Hae Young Song; Young Kyeung Kim; Haiyoung Jung; Young-Jun Park; Suk Ran Yoon; Sei-Ryang Oh; Tae-Don Kim; Inpyo Choi

doi:10.1371/journal.pone.0108913

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Peer-reviewed

Research Article

Integrated mRNA-MicroRNA Profiling of Human NK Cell Differentiation Identifies MiR-583 as a Negative Regulator of IL2Rγ Expression

Sohyun Yun ,

Contributed equally to this work with: Sohyun Yun, Su Ui Lee

Affiliation Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea
⨯
Su Ui Lee ,

Contributed equally to this work with: Sohyun Yun, Su Ui Lee

Affiliation Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang-eup, Republic of Korea
⨯
Jung Min Kim,

Affiliation NAR Center, Inc., Daejeon Oriental Hospital of Daejeon University, Daejeon, Republic of Korea
⨯
Hyun-Jun Lee,

Affiliation Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang-eup, Republic of Korea
⨯
Hae Young Song,

Affiliation Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea
⨯
Young Kyeung Kim,

Affiliation Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea
⨯
Haiyoung Jung,

Affiliation Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea
⨯
Young-Jun Park,

Affiliation Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea
⨯
Suk Ran Yoon,

Affiliation Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea
⨯
Sei-Ryang Oh,

Affiliation Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang-eup, Republic of Korea
⨯
Tae-Don Kim ,

* E-mail: tdkim@kribb.re.kr (TDK); ipchoi@kribb.re.kr (IC)

Affiliations Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea, Department of Functional Genomics, Korea University of Science and Technology, Daejeon, Republic of Korea
⨯
Inpyo Choi

* E-mail: tdkim@kribb.re.kr (TDK); ipchoi@kribb.re.kr (IC)

Affiliations Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea, Department of Functional Genomics, Korea University of Science and Technology, Daejeon, Republic of Korea
⨯

Integrated mRNA-MicroRNA Profiling of Human NK Cell Differentiation Identifies MiR-583 as a Negative Regulator of IL2Rγ Expression

Sohyun Yun,
Su Ui Lee,
Jung Min Kim,
Hyun-Jun Lee,
Hae Young Song,
Young Kyeung Kim,
Haiyoung Jung,
Young-Jun Park,
Suk Ran Yoon,
Sei-Ryang Oh

Published: October 14, 2014
https://doi.org/10.1371/journal.pone.0108913

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