Elevation of Proteasomal Substrate Levels Sensitizes Cells to Apoptosis Induced by Inhibition of Proteasomal Deubiquitinases

• Chao Sun,

  Affiliation Cancer Center Karolinska, Department of Oncology and Pathology, Karolinska Institute, Stockholm, Sweden

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• Peristera Roboti,

  Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

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• Marjo-Riitta Puumalainen,

  Current address: Institute of Pharmacology and Toxicology, University of Zürich-Vetsuisse, Zürich, Switzerland

  Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

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• Mårten Fryknäs,

  Affiliation Department of Medical Sciences, Division of Clinical Pharmacology, Uppsala University, Uppsala, Sweden

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• Xin Wang,

  Affiliation Cancer Center Karolinska, Department of Oncology and Pathology, Karolinska Institute, Stockholm, Sweden

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• Padraig D'Arcy,

  Affiliation Cancer Center Karolinska, Department of Oncology and Pathology, Karolinska Institute, Stockholm, Sweden

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• Malin Hult,

  Affiliation Center for Inherited Metabolic Diseases, Karolinska University Hospital, Stockholm, Sweden

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• Stephen High,

  Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

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• Stig Linder,

  Affiliation Cancer Center Karolinska, Department of Oncology and Pathology, Karolinska Institute, Stockholm, Sweden

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• Eileithyia Swanton

  * E-mail: lisa.swanton@manchester.ac.uk

  Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

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