The Truncate Mutation of Notch2 Enhances Cell Proliferation through Activating the NF-κB Signal Pathway in the Diffuse Large B-Cell Lymphomas

Xinxia Zhang; Yaoyao Shi; Yuanyuan Weng; Qian Lai; Taobo Luo; Jing Zhao; Guoping Ren; Wande Li; Hongyang Pan; Yuehai Ke; Wei Zhang; Qiang He; Qingqing Wang; Ren Zhou

doi:10.1371/journal.pone.0108747

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Open Access

Peer-reviewed

Research Article

The Truncate Mutation of Notch2 Enhances Cell Proliferation through Activating the NF-κB Signal Pathway in the Diffuse Large B-Cell Lymphomas

Xinxia Zhang,

Affiliation Department of Pathology and Pathophysiology, Institute of Pathology and Forensic Medicine, Zhejiang University School of Medicine, Hangzhou, China
⨯
Yaoyao Shi,

Affiliation Department of Pathology and Pathophysiology, Institute of Pathology and Forensic Medicine, Zhejiang University School of Medicine, Hangzhou, China
⨯
Yuanyuan Weng,

Affiliation Department of Pathology and Pathophysiology, Institute of Pathology and Forensic Medicine, Zhejiang University School of Medicine, Hangzhou, China
⨯
Qian Lai,

Affiliation Department of Pathology and Pathophysiology, Institute of Pathology and Forensic Medicine, Zhejiang University School of Medicine, Hangzhou, China
⨯
Taobo Luo,

Affiliation Department of Pathology and Pathophysiology, Institute of Pathology and Forensic Medicine, Zhejiang University School of Medicine, Hangzhou, China
⨯
Jing Zhao,

Affiliation Department of Pathology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Guoping Ren,

Affiliation Department of Pathology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⨯
Wande Li,

Affiliation Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯
Hongyang Pan,

Affiliations Department of Pathology and Pathophysiology, Institute of Pathology and Forensic Medicine, Zhejiang University School of Medicine, Hangzhou, China, Epitomics (Hangzhou) Inc., Hangzhou, China
⨯
Yuehai Ke,

Affiliation Department of Pathology and Pathophysiology, Institute of Pathology and Forensic Medicine, Zhejiang University School of Medicine, Hangzhou, China
⨯
Wei Zhang,

Affiliation Department of Pathology and Pathophysiology, Institute of Pathology and Forensic Medicine, Zhejiang University School of Medicine, Hangzhou, China
⨯
Qiang He,

Affiliation Zhejiang Province People's Hospital, Hangzhou, China
⨯
Qingqing Wang,

Affiliation Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, China
⨯
Ren Zhou

* E-mail: zhouren@zju.edu.cn

Affiliation Department of Pathology and Pathophysiology, Institute of Pathology and Forensic Medicine, Zhejiang University School of Medicine, Hangzhou, China
⨯

The Truncate Mutation of Notch2 Enhances Cell Proliferation through Activating the NF-κB Signal Pathway in the Diffuse Large B-Cell Lymphomas

Xinxia Zhang,
Yaoyao Shi,
Yuanyuan Weng,
Qian Lai,
Taobo Luo,
Jing Zhao,
Guoping Ren,
Wande Li,
Hongyang Pan,
Yuehai Ke

Published: October 14, 2014
https://doi.org/10.1371/journal.pone.0108747

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Cell proliferation
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