CD4+ T Cells Expressing Latency-Associated Peptide and Foxp3 Are an Activated Subgroup of Regulatory T Cells Enriched in Patients with Colorectal Cancer

Jayashri Mahalingam; Chun-Yen Lin; Jy-Ming Chiang; Po-Jung Su; Yu-Yi Chu; Hsin-Yi Lai; Jian-He Fang; Ching-Tai Huang; Yung-Chang Lin

doi:10.1371/journal.pone.0108554

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Open Access

Peer-reviewed

Research Article

CD4⁺ T Cells Expressing Latency-Associated Peptide and Foxp3 Are an Activated Subgroup of Regulatory T Cells Enriched in Patients with Colorectal Cancer

Jayashri Mahalingam,

Affiliations College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan, Department of Gastroenterology-Hepatology, Linkou Medical Centre, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
⨯
Chun-Yen Lin,

Affiliations College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan, Department of Gastroenterology-Hepatology, Linkou Medical Centre, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
⨯
Jy-Ming Chiang,

Affiliations College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan, Colorectal Surgery Section, Department of Surgery, Linkou Medical Centre, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
⨯
Po-Jung Su,

Affiliation Department of Hematology-Oncology, Linkou Medical Centre, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
⨯
Yu-Yi Chu,

Affiliation Department of Hematology-Oncology, Linkou Medical Centre, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
⨯
Hsin-Yi Lai,

Affiliation College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan
⨯
Jian-He Fang,

Affiliation Department of Gastroenterology-Hepatology, Linkou Medical Centre, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
⨯
Ching-Tai Huang,

Affiliations College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan, Department of Infectious Diseases, Linkou Medical Centre, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
⨯
Yung-Chang Lin

* E-mail: yclinof@adm.cgmh.org

Affiliations College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan, Department of Hematology-Oncology, Linkou Medical Centre, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
⨯

CD4⁺ T Cells Expressing Latency-Associated Peptide and Foxp3 Are an Activated Subgroup of Regulatory T Cells Enriched in Patients with Colorectal Cancer

Jayashri Mahalingam,
Chun-Yen Lin,
Jy-Ming Chiang,
Po-Jung Su,
Yu-Yi Chu,
Hsin-Yi Lai,
Jian-He Fang,
Ching-Tai Huang,
Yung-Chang Lin

Published: September 30, 2014
https://doi.org/10.1371/journal.pone.0108554

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