The NOD2 p.Leu1007fsX1008 Mutation (rs2066847) Is a Stronger Predictor of the Clinical Course of Crohn's Disease than the FOXO3A Intron Variant rs12212067

Fabian Schnitzler; Matthias Friedrich; Christiane Wolf; Marianne Angelberger; Julia Diegelmann; Torsten Olszak; Florian Beigel; Cornelia Tillack; Johannes Stallhofer; Burkhard Göke; Jürgen Glas; Peter Lohse; Stephan Brand

doi:10.1371/journal.pone.0108503

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Peer-reviewed

Research Article

The NOD2 p.Leu1007fsX1008 Mutation (rs2066847) Is a Stronger Predictor of the Clinical Course of Crohn's Disease than the FOXO3A Intron Variant rs12212067

Fabian Schnitzler ,

Contributed equally to this work with: Fabian Schnitzler, Matthias Friedrich

Affiliation Department of Medicine II-Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯
Matthias Friedrich ,

Contributed equally to this work with: Fabian Schnitzler, Matthias Friedrich

Affiliations Department of Medicine II-Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany, Department of Preventive Dentistry and Periodontology, LMU, Munich, Germany
⨯
Christiane Wolf,

Affiliation Max-Planck-Institute of Psychiatry, Munich, Germany
⨯
Marianne Angelberger,

Affiliation Department of Medicine II-Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯
Julia Diegelmann,

Affiliation Department of Preventive Dentistry and Periodontology, LMU, Munich, Germany
⨯
Torsten Olszak,

Affiliation Department of Medicine II-Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯
Florian Beigel,

Affiliation Department of Medicine II-Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯
Cornelia Tillack,

Affiliation Department of Medicine II-Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯
Johannes Stallhofer,

Affiliation Department of Medicine II-Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯
Burkhard Göke,

Affiliation Department of Medicine II-Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯
Jürgen Glas,

Affiliation Department of Human Genetics, Rheinisch-Westfälische Technische Hochschule (RWTH), Aachen, Germany
⨯
Peter Lohse,

Current address: Institute of Laboratory Medicine and Human Genetics, Singen, Germany

Affiliation Department of Clinical Chemistry-Grosshadern, LMU, Munich, Germany
⨯
Stephan Brand

* E-mail: stephan.brand@med.uni-muenchen.de

Affiliation Department of Medicine II-Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯

The NOD2 p.Leu1007fsX1008 Mutation (rs2066847) Is a Stronger Predictor of the Clinical Course of Crohn's Disease than the FOXO3A Intron Variant rs12212067

Fabian Schnitzler,
Matthias Friedrich,
Christiane Wolf,
Marianne Angelberger,
Julia Diegelmann,
Torsten Olszak,
Florian Beigel,
Cornelia Tillack,
Johannes Stallhofer,
Burkhard Göke

Published: November 3, 2014
https://doi.org/10.1371/journal.pone.0108503

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Single nucleotide polymorphisms
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