PTEN Redundancy: Overexpressing lpten, a Homolog of Dictyostelium discoideum ptenA, the Ortholog of Human PTEN, Rescues All Behavioral Defects of the Mutant ptenA−

Daniel F. Lusche; Deborah Wessels; Nicole A. Richardson; Kanoe B. Russell; Brett M. Hanson; Benjamin A. Soll; Benjamin H. Lin; David R. Soll

doi:10.1371/journal.pone.0108495

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Research Article

PTEN Redundancy: Overexpressing lpten, a Homolog of Dictyostelium discoideum ptenA, the Ortholog of Human PTEN, Rescues All Behavioral Defects of the Mutant ptenA⁻

Daniel F. Lusche,

Affiliation Monoclonal Antibody Research Institute and Developmental Studies Hybridoma Bank, Department of Biology, The University of Iowa, Iowa City, Iowa, United States of America
⨯
Deborah Wessels,

Affiliation Monoclonal Antibody Research Institute and Developmental Studies Hybridoma Bank, Department of Biology, The University of Iowa, Iowa City, Iowa, United States of America
⨯
Nicole A. Richardson,

Affiliation Monoclonal Antibody Research Institute and Developmental Studies Hybridoma Bank, Department of Biology, The University of Iowa, Iowa City, Iowa, United States of America
⨯
Kanoe B. Russell,

Affiliation Monoclonal Antibody Research Institute and Developmental Studies Hybridoma Bank, Department of Biology, The University of Iowa, Iowa City, Iowa, United States of America
⨯
Brett M. Hanson,

Affiliation Monoclonal Antibody Research Institute and Developmental Studies Hybridoma Bank, Department of Biology, The University of Iowa, Iowa City, Iowa, United States of America
⨯
Benjamin A. Soll,

Affiliation Monoclonal Antibody Research Institute and Developmental Studies Hybridoma Bank, Department of Biology, The University of Iowa, Iowa City, Iowa, United States of America
⨯
Benjamin H. Lin,

Affiliation Monoclonal Antibody Research Institute and Developmental Studies Hybridoma Bank, Department of Biology, The University of Iowa, Iowa City, Iowa, United States of America
⨯
David R. Soll

* E-mail: david-soll@uiowa.edu

Affiliation Monoclonal Antibody Research Institute and Developmental Studies Hybridoma Bank, Department of Biology, The University of Iowa, Iowa City, Iowa, United States of America
⨯

PTEN Redundancy: Overexpressing lpten, a Homolog of Dictyostelium discoideum ptenA, the Ortholog of Human PTEN, Rescues All Behavioral Defects of the Mutant ptenA⁻

Daniel F. Lusche,
Deborah Wessels,
Nicole A. Richardson,
Kanoe B. Russell,
Brett M. Hanson,
Benjamin A. Soll,
Benjamin H. Lin,
David R. Soll

Published: September 23, 2014
https://doi.org/10.1371/journal.pone.0108495

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Chemotaxis
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Cell motility
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Dictyostelium discoideum
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Reverse transcriptase-polymerase chain reaction
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Hyperexpression techniques
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