Pharmacologic Inhibition of MLK3 Kinase Activity Blocks the In Vitro Migratory Capacity of Breast Cancer Cells but Has No Effect on Breast Cancer Brain Metastasis in a Mouse Xenograft Model

• Kun Hyoe Rhoo,

  Affiliation Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America

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• Megan Granger,

  Current address: Upstate Stem Cell cGMP Facility, University of Rochester Medical Center, Rochester, New York, United States of America

  Affiliation Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America

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• Joynita Sur,

  Current address: Flaum Eye Institute, University of Rochester Medical Center, Rochester, New York, United States of America

  Affiliation Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America

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• Changyong Feng,

  Affiliation Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, New York, United States of America

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• Harris A. Gelbard,

  Affiliations Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America, Center for Neural Development and Disease, and Departments of Pediatrics and Neurology, University of Rochester Medical Center, Rochester, New York, United States of America

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• Stephen Dewhurst,

  Affiliation Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America

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• Oksana Polesskaya

  * E-mail: Oksana_Polesskaya@urmc.rochester.edu

  Affiliation Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America

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