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Open Access
Peer-reviewed
Research Article
Improving Mycobacterium bovis Bacillus Calmette-Guèrin as a Vaccine Delivery Vector for Viral Antigens by Incorporation of Glycolipid Activators of NKT Cells
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Manjunatha M. Venkataswamy ,
Contributed equally to this work with: Manjunatha M. Venkataswamy, Tony W. Ng
Affiliations Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America, National Institute of Mental Health and Neuroscience, Bangalore, Karnataka, India
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Tony W. Ng ,
Contributed equally to this work with: Manjunatha M. Venkataswamy, Tony W. Ng
Affiliation Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America
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Shalu S. Kharkwal,
Affiliation Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America
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Leandro J. Carreño,
Affiliations Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America, Millennium Institute on Immunology and Immunotherapy, Facultad de Medicina, Universidad de Chile, Santiago, Chile
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Alison J. Johnson,
Affiliation Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America
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Shajo Kunnath-Velayudhan,
Affiliation Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America
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Zheng Liu,
Affiliation Department of Chemistry and Biochemistry, Queens College of City University of New York, Flushing, New York, United States of America
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Robert Bittman,
Affiliation Department of Chemistry and Biochemistry, Queens College of City University of New York, Flushing, New York, United States of America
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Peter J. Jervis,
Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom
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Liam R. Cox,
Affiliation School of Chemistry, University of Birmingham, Edgbaston, Birmingham, United Kingdom
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Gurdyal S. Besra,
Affiliation School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom
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Xiangshu Wen,
Affiliation Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
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Weiming Yuan,
Affiliation Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
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Moriya Tsuji,
Affiliation Aaron Diamond AIDS Research Center, Rockefeller University, New York, New York, United States of America
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Xiangming Li,
Affiliation Aaron Diamond AIDS Research Center, Rockefeller University, New York, New York, United States of America
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David D. Ho,
Affiliation Aaron Diamond AIDS Research Center, Rockefeller University, New York, New York, United States of America
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John Chan,
Affiliation Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, United States of America
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Sunhee Lee,
Affiliation Duke University Medical Center, Durham, North Carolina, United States of America
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Richard Frothingham,
Affiliation Duke University Medical Center, Durham, North Carolina, United States of America
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Barton F. Haynes,
Affiliation Duke University Medical Center, Durham, North Carolina, United States of America
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Michael W. Panas,
Current address: Department of Microbiology and Immunology, Stanford Medical School, Palo Alto, California, United States of America
Affiliation Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Geoffrey O. Gillard,
Current address: Biogen Idec Incorporated, Cambridge, Massachusetts, United States of America
Affiliation Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Jaimie D. Sixsmith,
Affiliation Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Birgit Korioth-Schmitz,
Affiliation Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Joern E. Schmitz,
Affiliation Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Michelle H. Larsen,
Affiliations Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America, Howard Hughes Medical Institute, Albert Einstein College of Medicine, Bronx, New York, United States of America
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William R. Jacobs Jr,
Affiliations Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America, Howard Hughes Medical Institute, Albert Einstein College of Medicine, Bronx, New York, United States of America
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Steven A. Porcelli
* E-mail: steven.porcelli@einstein.yu.edu
Affiliations Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, United States of America
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Improving Mycobacterium bovis Bacillus Calmette-Guèrin as a Vaccine Delivery Vector for Viral Antigens by Incorporation of Glycolipid Activators of NKT Cells
- Manjunatha M. Venkataswamy,
- Tony W. Ng,
- Shalu S. Kharkwal,
- Leandro J. Carreño,
- Alison J. Johnson,
- Shajo Kunnath-Velayudhan,
- Zheng Liu,
- Robert Bittman,
- Peter J. Jervis,
- Liam R. Cox
- Published: September 25, 2014
- https://doi.org/10.1371/journal.pone.0108383