Large-Scaled Metabolic Profiling of Human Dermal Fibroblasts Derived from Pseudoxanthoma Elasticum Patients and Healthy Controls

Open Access

Peer-reviewed

Research Article

Patricia Kuzaj,

Affiliation Institut für Laboratoriums- und Transfusionsmedizin, Herz- und Diabeteszentrum Nordrhein-Westfalen, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen, Germany
⨯
Joachim Kuhn,

Affiliation Institut für Laboratoriums- und Transfusionsmedizin, Herz- und Diabeteszentrum Nordrhein-Westfalen, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen, Germany
⨯
Ryan D. Michalek,

Affiliation Metabolon, Inc., Durham, North Carolina, United States of America
⨯
Edward D. Karoly,

Affiliation Metabolon, Inc., Durham, North Carolina, United States of America
⨯
Isabel Faust,

Affiliation Institut für Laboratoriums- und Transfusionsmedizin, Herz- und Diabeteszentrum Nordrhein-Westfalen, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen, Germany
⨯
Mareike Dabisch-Ruthe,

Affiliation Institut für Laboratoriums- und Transfusionsmedizin, Herz- und Diabeteszentrum Nordrhein-Westfalen, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen, Germany
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Cornelius Knabbe,

Affiliation Institut für Laboratoriums- und Transfusionsmedizin, Herz- und Diabeteszentrum Nordrhein-Westfalen, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen, Germany
⨯
Doris Hendig

* E-mail: dhendig@hdz-nrw.de

Affiliation Institut für Laboratoriums- und Transfusionsmedizin, Herz- und Diabeteszentrum Nordrhein-Westfalen, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen, Germany
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Fibroblasts
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Cell metabolism
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Guanine
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Adenosine
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Fatty acids
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Xenobiotic metabolism
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Gene expression
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Small interfering RNA
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