HIF-2α Regulates NANOG Expression in Human Embryonic Stem Cells following Hypoxia and Reoxygenation through the Interaction with an Oct-Sox Cis Regulatory Element

Open Access

Peer-reviewed

Research Article

Raffaella Petruzzelli,

Affiliation Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯
David R. Christensen,

Affiliation Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯
Kate L. Parry,

Affiliation Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯
Tilman Sanchez-Elsner,

Affiliation Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯
Franchesca D. Houghton

* E-mail: F.D.Houghton@soton.ac.uk

Affiliation Centre for Human Development, Stem Cells and Regeneration, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯

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Hypoxia
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Chromatin
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Pluripotency
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Luciferase
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DNA transcription
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Binding analysis
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Epigenetics
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Transcriptional control
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