Optimizations of SiRNA Design for the Activation of Gene Transcription by Targeting the TATA-Box Motif

Miaomiao Fan; Yijun Zhang; Zhuoqiong Huang; Jun Liu; Xuemin Guo; Hui Zhang; Haihua Luo

doi:10.1371/journal.pone.0108253

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Open Access

Peer-reviewed

Research Article

Optimizations of SiRNA Design for the Activation of Gene Transcription by Targeting the TATA-Box Motif

Miaomiao Fan ,

Contributed equally to this work with: Miaomiao Fan, Yijun Zhang

Affiliations Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯
Yijun Zhang ,

Contributed equally to this work with: Miaomiao Fan, Yijun Zhang

Affiliations Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯
Zhuoqiong Huang,

Affiliations Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯
Jun Liu,

Affiliations Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯
Xuemin Guo,

Affiliations Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯
Hui Zhang ,

* E-mail: zhangh92@mail.sysu.edu.cn (HZ); luohh@mail.sysu.edu.cn (HL)

Affiliations Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯
Haihua Luo

* E-mail: zhangh92@mail.sysu.edu.cn (HZ); luohh@mail.sysu.edu.cn (HL)

Affiliations Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯

Optimizations of SiRNA Design for the Activation of Gene Transcription by Targeting the TATA-Box Motif

Miaomiao Fan,
Yijun Zhang,
Zhuoqiong Huang,
Jun Liu,
Xuemin Guo,
Hui Zhang,
Haihua Luo

Published: September 24, 2014
https://doi.org/10.1371/journal.pone.0108253

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