Loss of the Thioredoxin Reductase Trr1 Suppresses the Genomic Instability of Peroxiredoxin tsa1 Mutants

Sandrine Ragu; Michèle Dardalhon; Sushma Sharma; Ismail Iraqui; Géraldine Buhagiar-Labarchède; Virginie Grondin; Guy Kienda; Laurence Vernis; Roland Chanet; Richard D. Kolodner; Meng-Er Huang; Gérard Faye

doi:10.1371/journal.pone.0108123

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Open Access

Peer-reviewed

Research Article

Loss of the Thioredoxin Reductase Trr1 Suppresses the Genomic Instability of Peroxiredoxin tsa1 Mutants

Sandrine Ragu,

Current address: Institut Gustave Roussy, UMR8200, Villejuif, France

Affiliations Centre National de la Recherche Scientifique, UMR3348, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Michèle Dardalhon,

Affiliations Centre National de la Recherche Scientifique, UMR3348, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Sushma Sharma,

Affiliation Department of Medical Biochemistry and Biophysics, Umea University, Umea, Sweden
⨯
Ismail Iraqui,

Affiliations Centre National de la Recherche Scientifique, UMR3348, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Géraldine Buhagiar-Labarchède,

Affiliations Centre National de la Recherche Scientifique, UMR3348, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Virginie Grondin,

Current address: INRA Versailles, Unité Pessac, Versailles, France

Affiliations Centre National de la Recherche Scientifique, UMR3348, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Guy Kienda,

Affiliations Centre National de la Recherche Scientifique, UMR3348, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Laurence Vernis,

Affiliations Centre National de la Recherche Scientifique, UMR3348, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Roland Chanet,

Affiliations Centre National de la Recherche Scientifique, UMR3348, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Richard D. Kolodner,

Affiliation Ludwig Institute for Cancer Research, University of California School of Medicine San Diego, La Jolla, California, United States of America
⨯
Meng-Er Huang ,

* E-mail: meng-er.huang@curie.fr

Affiliations Centre National de la Recherche Scientifique, UMR3348, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Gérard Faye

Affiliations Centre National de la Recherche Scientifique, UMR3348, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯

Loss of the Thioredoxin Reductase Trr1 Suppresses the Genomic Instability of Peroxiredoxin tsa1 Mutants

Sandrine Ragu,
Michèle Dardalhon,
Sushma Sharma,
Ismail Iraqui,
Géraldine Buhagiar-Labarchède,
Virginie Grondin,
Guy Kienda,
Laurence Vernis,
Roland Chanet,
Richard D. Kolodner

Published: September 23, 2014
https://doi.org/10.1371/journal.pone.0108123

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DNA damage
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Oxidation-reduction reactions
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