CTLA-4 Modulates the Differentiation of Inducible Foxp3+ Treg Cells but IL-10 Mediates Their Function in Experimental Autoimmune Encephalomyelitis

Open Access

Peer-reviewed

Research Article

CTLA-4 Modulates the Differentiation of Inducible Foxp3⁺ Treg Cells but IL-10 Mediates Their Function in Experimental Autoimmune Encephalomyelitis

Johan Verhagen ,

* E-mail: Johan.Verhagen@bristol.ac.uk

Affiliation School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom
⨯
Leona Gabryšová,

Current address: Division of Immunoregulation, MRC National Institute for Medical Research, London, United Kingdom

Affiliation School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom
⨯
Ella R. Shepard,

Affiliation School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom
⨯
David C. Wraith

Affiliation School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom
⨯

T cells
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Regulatory T cells
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Cell differentiation
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Autoimmune diseases
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Adoptive transfer
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Mouse models
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Spleen
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Flow cytometry
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