PCR-Based Assays versus Direct Sequencing for Evaluating the Effect of KRAS Status on Anti-EGFR Treatment Response in Colorectal Cancer Patients: A Systematic Review and Meta-Analysis

Open Access

Peer-reviewed

Research Article

Lianfeng Shan,

Affiliation Department of Mathematics, College of Basic Medical Sciences, China Medical University, Shenyang, China
⨯
Ming Li,

Affiliation Department of Mathematics, College of Basic Medical Sciences, China Medical University, Shenyang, China
⨯
Jianzhong Ma ,

* E-mail: jzma@mail.cmu.edu.cn (JM); hdzhang@mail.cmu.edu.cn (HZ)

Affiliation Department of Mathematics, College of Basic Medical Sciences, China Medical University, Shenyang, China
⨯
Huidan Zhang

* E-mail: jzma@mail.cmu.edu.cn (JM); hdzhang@mail.cmu.edu.cn (HZ)

Affiliation Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang, China
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Cancer treatment
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Direct sequencing
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Polymerase chain reaction
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Chemotherapy
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Colorectal cancer
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Genotyping
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Metaanalysis
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Mutation detection
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