HBx Inhibits CYP2E1 Gene Expression via Downregulating HNF4α in Human Hepatoma Cells

Open Access

Peer-reviewed

Research Article

Hongming Liu ,

Contributed equally to this work with: Hongming Liu, Guiyu Lou

Affiliation Department of Hepatobiliary Surgery, Daping Hospital & Institute of Surgery Research, The Third Military Medical University, Chongqing, China
⨯
Guiyu Lou ,

Contributed equally to this work with: Hongming Liu, Guiyu Lou

Affiliation Department of Biochemistry and Molecular Biology, The Third Military Medical University, Chongqing, China
⨯
Chongyi Li,

Affiliation Department of Biochemistry and Molecular Biology, The Third Military Medical University, Chongqing, China
⨯
Xiaodong Wang,

Affiliations Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Chongqing Biomean Technology Co., Ltd, Chongqing, China
⨯
Arthur I. Cederbaum,

Affiliation Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
⨯
Lixia Gan ,

* E-mail: ganlixia@yahoo.com (LG); xiebin313@126.com (BX)

Affiliation Department of Biochemistry and Molecular Biology, The Third Military Medical University, Chongqing, China
⨯
Bin Xie

* E-mail: ganlixia@yahoo.com (LG); xiebin313@126.com (BX)

Affiliation Department of Hepatobiliary Surgery, Daping Hospital & Institute of Surgery Research, The Third Military Medical University, Chongqing, China
⨯

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Hepatocellular carcinoma
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Gene expression
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DNA-binding proteins
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Transfection
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Hepatocytes
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Plasmid construction
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Mouse models
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Hyperexpression techniques
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