HIF-1α Signaling Activation by Post-Ischemia Treatment with Astragaloside IV Attenuates Myocardial Ischemia-Reperfusion Injury

Jingwen Si; Ning Wang; Huan Wang; Juan Xie; Jian Yang; Hui Yi; Zixuan Shi; Jing Ma; Wen Wang; Lifang Yang; Shiqiang Yu; Junchang Li

doi:10.1371/journal.pone.0107832

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Open Access

Peer-reviewed

Research Article

HIF-1α Signaling Activation by Post-Ischemia Treatment with Astragaloside IV Attenuates Myocardial Ischemia-Reperfusion Injury

Jingwen Si ,

Contributed equally to this work with: Jingwen Si, Ning Wang, Huan Wang

Affiliation Department of Traditional Chinese Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an City, Shaanxi Province, China
⨯
Ning Wang ,

Contributed equally to this work with: Jingwen Si, Ning Wang, Huan Wang

Affiliation Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an City, Shaanxi Province, China
⨯
Huan Wang ,

Contributed equally to this work with: Jingwen Si, Ning Wang, Huan Wang

Affiliation Department of Dermatology, Tangdu Hospital, The Fourth Military Medical University, Xi'an City, Shaanxi Province, China
⨯
Juan Xie,

Affiliation Department of Traditional Chinese Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an City, Shaanxi Province, China
⨯
Jian Yang,

Affiliation Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an City, Shaanxi Province, China
⨯
Hui Yi,

Affiliation Department of Nephropathy and Immunology, BaYi Childrens Hospital of The General Military Hospital of Beijing PLA, Beijing, China
⨯
Zixuan Shi,

Affiliation Department of Traditional Chinese Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an City, Shaanxi Province, China
⨯
Jing Ma,

Affiliation Department of Traditional Chinese Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an City, Shaanxi Province, China
⨯
Wen Wang,

Affiliation Department of Traditional Chinese Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an City, Shaanxi Province, China
⨯
Lifang Yang ,

* E-mail: jingwensi111@126.com (JCL); shiqiangyu210@126.com (SQY); yangjian1212@hotmail.com (LFY)

Affiliation Department of Anesthesiology, Xijing Hospital, The Fourth Military Medical University, Xi'an City, Shaanxi Province, China
⨯
Shiqiang Yu ,

* E-mail: jingwensi111@126.com (JCL); shiqiangyu210@126.com (SQY); yangjian1212@hotmail.com (LFY)

Affiliation Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an City, Shaanxi Province, China
⨯
Junchang Li

* E-mail: jingwensi111@126.com (JCL); shiqiangyu210@126.com (SQY); yangjian1212@hotmail.com (LFY)

Affiliation Department of Traditional Chinese Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an City, Shaanxi Province, China
⨯

HIF-1α Signaling Activation by Post-Ischemia Treatment with Astragaloside IV Attenuates Myocardial Ischemia-Reperfusion Injury

Jingwen Si,
Ning Wang,
Huan Wang,
Juan Xie,
Jian Yang,
Hui Yi,
Zixuan Shi,
Jing Ma,
Wen Wang,
Lifang Yang

Published: September 19, 2014
https://doi.org/10.1371/journal.pone.0107832

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