Prohibitin-Mediated Lifespan and Mitochondrial Stress Implicate SGK-1, Insulin/IGF and mTORC2 in C. elegans

Roxani Gatsi; Bettina Schulze; María Jesús Rodríguez-Palero; Blanca Hernando-Rodríguez; Ralf Baumeister; Marta Artal-Sanz

doi:10.1371/journal.pone.0107671

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Research Article

Prohibitin-Mediated Lifespan and Mitochondrial Stress Implicate SGK-1, Insulin/IGF and mTORC2 in C. elegans

Roxani Gatsi,

Affiliation CABD, Centro Andaluz de Biología del Desarrollo, CSIC-Universidad Pablo de Olavide-Junta de Andalucía, Sevilla, Spain
⨯
Bettina Schulze,

Affiliations Centre for Biological Signalling Studies (BIOSS), Albert-Ludwigs-University of Freiburg, Freiburg, Germany, Laboratory for Bioinformatics and Molecular Genetics, Faculty of Biology, Albert-Ludwigs-University of Freiburg, Freiburg, Germany
⨯
María Jesús Rodríguez-Palero,

Affiliation CABD, Centro Andaluz de Biología del Desarrollo, CSIC-Universidad Pablo de Olavide-Junta de Andalucía, Sevilla, Spain
⨯
Blanca Hernando-Rodríguez,

Affiliation CABD, Centro Andaluz de Biología del Desarrollo, CSIC-Universidad Pablo de Olavide-Junta de Andalucía, Sevilla, Spain
⨯
Ralf Baumeister,

Affiliations Centre for Biological Signalling Studies (BIOSS), Albert-Ludwigs-University of Freiburg, Freiburg, Germany, Laboratory for Bioinformatics and Molecular Genetics, Faculty of Biology, Albert-Ludwigs-University of Freiburg, Freiburg, Germany, Center for Biochemistry and Molecular Cell Research, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany
⨯
Marta Artal-Sanz

* E-mail: martsan@upo.es

Affiliations CABD, Centro Andaluz de Biología del Desarrollo, CSIC-Universidad Pablo de Olavide-Junta de Andalucía, Sevilla, Spain, Centre for Biological Signalling Studies (BIOSS), Albert-Ludwigs-University of Freiburg, Freiburg, Germany, Laboratory for Bioinformatics and Molecular Genetics, Faculty of Biology, Albert-Ludwigs-University of Freiburg, Freiburg, Germany
⨯

Prohibitin-Mediated Lifespan and Mitochondrial Stress Implicate SGK-1, Insulin/IGF and mTORC2 in C. elegans

Roxani Gatsi,
Bettina Schulze,
María Jesús Rodríguez-Palero,
Blanca Hernando-Rodríguez,
Ralf Baumeister,
Marta Artal-Sanz

Published: September 29, 2014
https://doi.org/10.1371/journal.pone.0107671

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