Pro-Inflammatory and Pro-Oxidant Status of Pancreatic Islet In Vitro Is Controlled by TLR-4 and HO-1 Pathways

Kevin Vivot; Allan Langlois; William Bietiger; Stéphanie Dal; Elodie Seyfritz; Michel Pinget; Nathalie Jeandidier; Elisa Maillard; Jean-Pierre Gies; Séverine Sigrist

doi:10.1371/journal.pone.0107656

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Peer-reviewed

Research Article

Pro-Inflammatory and Pro-Oxidant Status of Pancreatic Islet In Vitro Is Controlled by TLR-4 and HO-1 Pathways

Kevin Vivot,

Affiliation DIATHEC, EA 7294, Centre Européen d'Etude du Diabète, Université de Strasbourg, Fédération de Médecine Translationnelle, Strasbourg, France
⨯
Allan Langlois,

Affiliation DIATHEC, EA 7294, Centre Européen d'Etude du Diabète, Université de Strasbourg, Fédération de Médecine Translationnelle, Strasbourg, France
⨯
William Bietiger,

Affiliation DIATHEC, EA 7294, Centre Européen d'Etude du Diabète, Université de Strasbourg, Fédération de Médecine Translationnelle, Strasbourg, France
⨯
Stéphanie Dal,

Affiliation DIATHEC, EA 7294, Centre Européen d'Etude du Diabète, Université de Strasbourg, Fédération de Médecine Translationnelle, Strasbourg, France
⨯
Elodie Seyfritz,

Affiliation DIATHEC, EA 7294, Centre Européen d'Etude du Diabète, Université de Strasbourg, Fédération de Médecine Translationnelle, Strasbourg, France
⨯
Michel Pinget,

Affiliations DIATHEC, EA 7294, Centre Européen d'Etude du Diabète, Université de Strasbourg, Fédération de Médecine Translationnelle, Strasbourg, France, Structure d'Endocrinologie, Diabète –Nutrition et Addictologie, Pôle NUDE, Hôpitaux Universitaires de Strasbourg, (HUS), Strasbourg, France
⨯
Nathalie Jeandidier,

Affiliations DIATHEC, EA 7294, Centre Européen d'Etude du Diabète, Université de Strasbourg, Fédération de Médecine Translationnelle, Strasbourg, France, Structure d'Endocrinologie, Diabète –Nutrition et Addictologie, Pôle NUDE, Hôpitaux Universitaires de Strasbourg, (HUS), Strasbourg, France
⨯
Elisa Maillard,

Affiliation DIATHEC, EA 7294, Centre Européen d'Etude du Diabète, Université de Strasbourg, Fédération de Médecine Translationnelle, Strasbourg, France
⨯
Jean-Pierre Gies,

Affiliation UMR 7034 CNRS, Faculté de Pharmacie, Université de Strasbourg, Illkirch, France
⨯
Séverine Sigrist

* E-mail: s.sigrist@ceed-diabete.org

Affiliation DIATHEC, EA 7294, Centre Européen d'Etude du Diabète, Université de Strasbourg, Fédération de Médecine Translationnelle, Strasbourg, France
⨯

Pro-Inflammatory and Pro-Oxidant Status of Pancreatic Islet In Vitro Is Controlled by TLR-4 and HO-1 Pathways

Kevin Vivot,
Allan Langlois,
William Bietiger,
Stéphanie Dal,
Elodie Seyfritz,
Michel Pinget,
Nathalie Jeandidier,
Elisa Maillard,
Jean-Pierre Gies,
Séverine Sigrist

Published: October 24, 2014
https://doi.org/10.1371/journal.pone.0107656

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Inflammation
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Macrophages
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Immune receptor signaling
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Toll-like receptors
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Islet transplantation
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