Sheep Lung Segmental Delivery Strategy Demonstrates Adenovirus Priming of Local Lung Responses to Bacterial LPS and the Role of Elafin as a Response Modulator

Open Access

Peer-reviewed

Research Article

Thomas I. Brown,

Affiliations University of Edinburgh, Medical School, Edinburgh, Scotland, United Kingdom, The Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, United Kingdom
⨯
David S. Collie ,

* E-mail: david.collie@ed.ac.uk

¶DSC and J-MS are joint senior authors on this work.

Affiliation The Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, United Kingdom
⨯
Darren J. Shaw,

Affiliation The Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, United Kingdom
⨯
Nina M. Rzechorzek,

Affiliation The Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, United Kingdom
⨯
Jean-Michel Sallenave

¶DSC and J-MS are joint senior authors on this work.

Affiliation University of Edinburgh, Medical School, Edinburgh, Scotland, United Kingdom
⨯

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Alveolar macrophages
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Adenoviruses
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Respiratory infections
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Lymphocytes
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Neutrophils
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Phagocytosis
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Sheep
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Lungs
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