Involvement of Tumor Macrophage HIFs in Chemotherapy Effectiveness: Mathematical Modeling of Oxygen, pH, and Glutathione

• Duan Chen,

  Affiliation Department of Mathematics and Statistics, University of North Carolina at Charlotte, Charlotte, North Carolina, United States of America

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• Andrey A. Bobko,

  Affiliation Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Amy C. Gross,

  Affiliation Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Randall Evans,

  Affiliation Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Clay B. Marsh,

  Affiliation Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Valery V. Khramtsov,

  Affiliation Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Timothy D. Eubank ,

  * E-mail: Tim.Eubank@osumc.edu (TDE); afriedman@math.osu.edu (AF)

  Affiliation Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• Avner Friedman

  * E-mail: Tim.Eubank@osumc.edu (TDE); afriedman@math.osu.edu (AF)

  Affiliations Mathematical Biosciences Institute, The Ohio State University, Columbus, Ohio, United States of America, Department of Mathematics, The Ohio State University, Columbus, Ohio, United States of America

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