Distribution of Intravenously Administered Acetylcholinesterase Inhibitor and Acetylcholinesterase Activity in the Adrenal Gland: 11C-Donepezil PET Study in the Normal Rat

Tadashi Watabe; Sadahiro Naka; Hayato Ikeda; Genki Horitsugi; Yasukazu Kanai; Kayako Isohashi; Mana Ishibashi; Hiroki Kato; Eku Shimosegawa; Hiroshi Watabe; Jun Hatazawa

doi:10.1371/journal.pone.0107427

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Open Access

Peer-reviewed

Research Article

Distribution of Intravenously Administered Acetylcholinesterase Inhibitor and Acetylcholinesterase Activity in the Adrenal Gland: ¹¹C-Donepezil PET Study in the Normal Rat

Tadashi Watabe ,

* E-mail: twatabe@mi.med.osaka-u.ac.jp

Affiliations Department of Molecular Imaging in Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, PET molecular Imaging Center, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Sadahiro Naka,

Affiliation Osaka University Hospital, Suita, Osaka, Japan
⨯
Hayato Ikeda,

Affiliation Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Genki Horitsugi,

Affiliation Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Yasukazu Kanai,

Affiliations Department of Molecular Imaging in Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, PET molecular Imaging Center, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Kayako Isohashi,

Affiliations PET molecular Imaging Center, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Mana Ishibashi,

Affiliation Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Hiroki Kato,

Affiliations PET molecular Imaging Center, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Eku Shimosegawa,

Affiliations PET molecular Imaging Center, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Hiroshi Watabe,

Current address: Cyclotron and Radioisotope Center, Tohoku University, Sendai, Miyagi, Japan

Affiliations Department of Molecular Imaging in Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, PET molecular Imaging Center, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
⨯
Jun Hatazawa

Affiliations PET molecular Imaging Center, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan
⨯

Distribution of Intravenously Administered Acetylcholinesterase Inhibitor and Acetylcholinesterase Activity in the Adrenal Gland: ¹¹C-Donepezil PET Study in the Normal Rat

Tadashi Watabe,
Sadahiro Naka,
Hayato Ikeda,
Genki Horitsugi,
Yasukazu Kanai,
Kayako Isohashi,
Mana Ishibashi,
Hiroki Kato,
Eku Shimosegawa,
Hiroshi Watabe

Published: September 16, 2014
https://doi.org/10.1371/journal.pone.0107427

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