Comprehensive Analysis of Preeclampsia-Associated DNA Methylation in the Placenta

Tianjiao Chu; Kimberly Bunce; Patricia Shaw; Varsha Shridhar; Andrew Althouse; Carl Hubel; David Peters

doi:10.1371/journal.pone.0107318

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Peer-reviewed

Research Article

Comprehensive Analysis of Preeclampsia-Associated DNA Methylation in the Placenta

Tianjiao Chu,

Affiliations Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Kimberly Bunce,

Affiliation Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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Patricia Shaw,

Affiliation Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Varsha Shridhar,

Affiliations Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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Andrew Althouse,

Affiliation Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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Carl Hubel,

Affiliations Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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David Peters

* E-mail: david.peters@mail.hgen.pitt.edu

Affiliations Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯

Comprehensive Analysis of Preeclampsia-Associated DNA Methylation in the Placenta

Tianjiao Chu,
Kimberly Bunce,
Patricia Shaw,
Varsha Shridhar,
Andrew Althouse,
Carl Hubel,
David Peters

Published: September 23, 2014
https://doi.org/10.1371/journal.pone.0107318

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DNA methylation
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Preeclampsia
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Placenta
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Pregnancy
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Gene expression
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X chromosomes
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Hierarchical clustering
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Hypertensive disorders in pregnancy
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