Age-Associated Epigenetic Upregulation of the FKBP5 Gene Selectively Impairs Stress Resiliency

Jonathan J. Sabbagh; John C. O'Leary III; Laura J. Blair; Torsten Klengel; Bryce A. Nordhues; Sarah N. Fontaine; Elisabeth B. Binder; Chad A. Dickey

doi:10.1371/journal.pone.0107241

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Peer-reviewed

Research Article

Age-Associated Epigenetic Upregulation of the FKBP5 Gene Selectively Impairs Stress Resiliency

Jonathan J. Sabbagh,

Affiliation Department of Molecular Medicine, Byrd Alzheimer's Research Institute, University of South Florida, Tampa, Florida, United States of America
⨯
John C. O'Leary III,

Affiliation Department of Molecular Medicine, Byrd Alzheimer's Research Institute, University of South Florida, Tampa, Florida, United States of America
⨯
Laura J. Blair,

Affiliation Department of Molecular Medicine, Byrd Alzheimer's Research Institute, University of South Florida, Tampa, Florida, United States of America
⨯
Torsten Klengel,

Affiliations Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, Unites States of America, Department of Translational Research, Max Planck Institute of Psychiatry, Munich, Germany
⨯
Bryce A. Nordhues,

Affiliation Department of Molecular Medicine, Byrd Alzheimer's Research Institute, University of South Florida, Tampa, Florida, United States of America
⨯
Sarah N. Fontaine,

Affiliation Department of Molecular Medicine, Byrd Alzheimer's Research Institute, University of South Florida, Tampa, Florida, United States of America
⨯
Elisabeth B. Binder,

Affiliations Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, Unites States of America, Department of Translational Research, Max Planck Institute of Psychiatry, Munich, Germany
⨯
Chad A. Dickey

* E-mail: cdickey@health.usf.edu

Affiliation Department of Molecular Medicine, Byrd Alzheimer's Research Institute, University of South Florida, Tampa, Florida, United States of America
⨯

Age-Associated Epigenetic Upregulation of the FKBP5 Gene Selectively Impairs Stress Resiliency

Jonathan J. Sabbagh,
John C. O'Leary III,
Laura J. Blair,
Torsten Klengel,
Bryce A. Nordhues,
Sarah N. Fontaine,
Elisabeth B. Binder,
Chad A. Dickey

Published: September 5, 2014
https://doi.org/10.1371/journal.pone.0107241

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