Pronounced Effects of HERG-Blockers E-4031 and Erythromycin on APD, Spatial APD Dispersion and Triangulation in Transgenic Long-QT Type 1 Rabbits

David Ziupa; Julia Beck; Gerlind Franke; Stefanie Perez Feliz; Maximilian Hartmann; Gideon Koren; Manfred Zehender; Christoph Bode; Michael Brunner; Katja E. Odening

doi:10.1371/journal.pone.0107210

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Peer-reviewed

Research Article

Pronounced Effects of HERG-Blockers E-4031 and Erythromycin on APD, Spatial APD Dispersion and Triangulation in Transgenic Long-QT Type 1 Rabbits

David Ziupa ,

Contributed equally to this work with: David Ziupa, Julia Beck

Affiliation Heart Center University of Freiburg, Department of Cardiology and Angiology I, Freiburg, Germany
⨯
Julia Beck ,

Contributed equally to this work with: David Ziupa, Julia Beck

Affiliation Heart Center University of Freiburg, Department of Cardiology and Angiology I, Freiburg, Germany
⨯
Gerlind Franke,

Affiliation Heart Center University of Freiburg, Department of Cardiology and Angiology I, Freiburg, Germany
⨯
Stefanie Perez Feliz,

Affiliation Heart Center University of Freiburg, Department of Cardiology and Angiology I, Freiburg, Germany
⨯
Maximilian Hartmann,

Affiliation Heart Center University of Freiburg, Department of Cardiology and Angiology I, Freiburg, Germany
⨯
Gideon Koren,

Affiliation Cardiovascular Research Center, Division of Cardiology, Rhode Island Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯
Manfred Zehender,

Affiliation Heart Center University of Freiburg, Department of Cardiology and Angiology I, Freiburg, Germany
⨯
Christoph Bode,

Affiliation Heart Center University of Freiburg, Department of Cardiology and Angiology I, Freiburg, Germany
⨯
Michael Brunner,

Affiliation Heart Center University of Freiburg, Department of Cardiology and Angiology I, Freiburg, Germany
⨯
Katja E. Odening

* E-mail: katja.odening@universitaets-herzzentrum.de

Affiliation Heart Center University of Freiburg, Department of Cardiology and Angiology I, Freiburg, Germany
⨯

Pronounced Effects of HERG-Blockers E-4031 and Erythromycin on APD, Spatial APD Dispersion and Triangulation in Transgenic Long-QT Type 1 Rabbits

David Ziupa,
Julia Beck,
Gerlind Franke,
Stefanie Perez Feliz,
Maximilian Hartmann,
Gideon Koren,
Manfred Zehender,
Christoph Bode,
Michael Brunner,
Katja E. Odening

Published: September 22, 2014
https://doi.org/10.1371/journal.pone.0107210

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