A Prolyl-Hydroxylase Inhibitor, Ethyl-3,4-Dihydroxybenzoate, Induces Cell Autophagy and Apoptosis in Esophageal Squamous Cell Carcinoma Cells via Up-Regulation of BNIP3 and N-myc Downstream-Regulated Gene-1

Open Access

Peer-reviewed

Research Article

Bo Han,

Affiliation State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
⨯
Wei Li,

Affiliation State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
⨯
Yulin Sun,

Affiliation State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
⨯
Lanping Zhou,

Affiliation State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
⨯
Yang Xu ,

* E-mail: zhaoxh@cicams.ac.cn (XZ); xuyang@cicams.ac.cn (YX)

Affiliation State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
⨯
Xiaohang Zhao

* E-mail: zhaoxh@cicams.ac.cn (XZ); xuyang@cicams.ac.cn (YX)

Affiliation State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
⨯

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Apoptosis
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Autophagic cell death
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Cancer treatment
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Esophageal cancer
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Gene expression
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Protein expression
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Mitochondria
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Cell cycle and cell division
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