Safety Assessment of Liver-Targeted Hydrodynamic Gene Delivery in Dogs

Kenya Kamimura; Tsutomu Kanefuji; Takeshi Yokoo; Hiroyuki Abe; Takeshi Suda; Yuji Kobayashi; Guisheng Zhang; Yutaka Aoyagi; Dexi Liu

doi:10.1371/journal.pone.0107203

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Open Access

Peer-reviewed

Research Article

Safety Assessment of Liver-Targeted Hydrodynamic Gene Delivery in Dogs

Kenya Kamimura ,

* E-mail: kenya–k@med.niigata–u.ac.jp (KK); dliu@uga.edu (DL)

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
⨯
Tsutomu Kanefuji,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
⨯
Takeshi Yokoo,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
⨯
Hiroyuki Abe,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
⨯
Takeshi Suda,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
⨯
Yuji Kobayashi,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
⨯
Guisheng Zhang,

Affiliation Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, United States of America
⨯
Yutaka Aoyagi,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan
⨯
Dexi Liu

* E-mail: kenya–k@med.niigata–u.ac.jp (KK); dliu@uga.edu (DL)

Affiliation Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, United States of America
⨯

Safety Assessment of Liver-Targeted Hydrodynamic Gene Delivery in Dogs

Kenya Kamimura,
Tsutomu Kanefuji,
Takeshi Yokoo,
Hiroyuki Abe,
Takeshi Suda,
Yuji Kobayashi,
Guisheng Zhang,
Yutaka Aoyagi,
Dexi Liu

Published: September 24, 2014
https://doi.org/10.1371/journal.pone.0107203

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