Mechanism of the pH-Induced Conformational Change in the Sensor Domain of the DraK Histidine Kinase via the E83, E105, and E107 Residues

Kwon Joo Yeo; Young-Soo Hong; Jun-Goo Jee; Jae Kyoung Lee; Hyo Jeong Kim; Jin-Wan Park; Eun-Hee Kim; Eunha Hwang; Sang-Yoon Kim; Eun-Gyeong Lee; Ohsuk Kwon; Hae-Kap Cheong

doi:10.1371/journal.pone.0107168

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Open Access

Peer-reviewed

Research Article

Mechanism of the pH-Induced Conformational Change in the Sensor Domain of the DraK Histidine Kinase via the E83, E105, and E107 Residues

Kwon Joo Yeo ,

Contributed equally to this work with: Kwon Joo Yeo, Young-Soo Hong

Affiliation Division of Magnetic Resonance, Korea Basic Science Institute (KBSI), Ochang, Chungbuk, Republic of Korea
⨯
Young-Soo Hong ,

Contributed equally to this work with: Kwon Joo Yeo, Young-Soo Hong

Affiliation Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Ochang, Chungbuk, Republic of Korea
⨯
Jun-Goo Jee,

Affiliation College of Pharmacy, Kyungpook National University, Kyungpook, Republic of Korea
⨯
Jae Kyoung Lee,

Affiliation Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Ochang, Chungbuk, Republic of Korea
⨯
Hyo Jeong Kim,

Affiliation Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Ochang, Chungbuk, Republic of Korea
⨯
Jin-Wan Park,

Affiliation Division of Magnetic Resonance, Korea Basic Science Institute (KBSI), Ochang, Chungbuk, Republic of Korea
⨯
Eun-Hee Kim,

Affiliation Division of Magnetic Resonance, Korea Basic Science Institute (KBSI), Ochang, Chungbuk, Republic of Korea
⨯
Eunha Hwang,

Affiliation Division of Magnetic Resonance, Korea Basic Science Institute (KBSI), Ochang, Chungbuk, Republic of Korea
⨯
Sang-Yoon Kim,

Affiliation Biochemicals and Synthetic Biology Research Center, KRIBB, Yuseong-Gu, Daejeon, Republic of Korea
⨯
Eun-Gyeong Lee,

Affiliation Biochemicals and Synthetic Biology Research Center, KRIBB, Yuseong-Gu, Daejeon, Republic of Korea
⨯
Ohsuk Kwon ,

* E-mail: haekap@kbsi.re.kr (H-KC); oskwon@kribb.re.kr (OK)

Affiliation Biochemicals and Synthetic Biology Research Center, KRIBB, Yuseong-Gu, Daejeon, Republic of Korea
⨯
Hae-Kap Cheong

* E-mail: haekap@kbsi.re.kr (H-KC); oskwon@kribb.re.kr (OK)

Affiliation Division of Magnetic Resonance, Korea Basic Science Institute (KBSI), Ochang, Chungbuk, Republic of Korea
⨯

Mechanism of the pH-Induced Conformational Change in the Sensor Domain of the DraK Histidine Kinase via the E83, E105, and E107 Residues

Kwon Joo Yeo,
Young-Soo Hong,
Jun-Goo Jee,
Jae Kyoung Lee,
Hyo Jeong Kim,
Jin-Wan Park,
Eun-Hee Kim,
Eunha Hwang,
Sang-Yoon Kim,
Eun-Gyeong Lee

Published: September 9, 2014
https://doi.org/10.1371/journal.pone.0107168

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