ALDH1A1 Maintains Ovarian Cancer Stem Cell-Like Properties by Altered Regulation of Cell Cycle Checkpoint and DNA Repair Network Signaling

Erhong Meng; Aparna Mitra; Kaushlendra Tripathi; Michael A. Finan; Jennifer Scalici; Steve McClellan; Luciana Madeira da Silva; Eddie Reed; Lalita A. Shevde; Komaraiah Palle; Rodney P. Rocconi

doi:10.1371/journal.pone.0107142

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Open Access

Peer-reviewed

Research Article

ALDH1A1 Maintains Ovarian Cancer Stem Cell-Like Properties by Altered Regulation of Cell Cycle Checkpoint and DNA Repair Network Signaling

Erhong Meng,

Affiliation University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States of America
⨯
Aparna Mitra,

Affiliation University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States of America
⨯
Kaushlendra Tripathi,

Affiliation University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States of America
⨯
Michael A. Finan,

Affiliation University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States of America
⨯
Jennifer Scalici,

Affiliation University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States of America
⨯
Steve McClellan,

Affiliation University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States of America
⨯
Luciana Madeira da Silva,

Affiliation University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States of America
⨯
Eddie Reed,

Affiliation National Institutes of Health, National Institute on Minority Health and Health Disparities, Bethesda, Maryland, United States of America
⨯
Lalita A. Shevde,

Affiliation University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Komaraiah Palle ,

* E-mail: kpalle@health.southalabama.edu (KP); rocconi@health.southalabama.edu (RPR)

Affiliation University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States of America
⨯
Rodney P. Rocconi

* E-mail: kpalle@health.southalabama.edu (KP); rocconi@health.southalabama.edu (RPR)

Affiliation University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States of America
⨯

ALDH1A1 Maintains Ovarian Cancer Stem Cell-Like Properties by Altered Regulation of Cell Cycle Checkpoint and DNA Repair Network Signaling

Erhong Meng,
Aparna Mitra,
Kaushlendra Tripathi,
Michael A. Finan,
Jennifer Scalici,
Steve McClellan,
Luciana Madeira da Silva,
Eddie Reed,
Lalita A. Shevde,
Komaraiah Palle

Published: September 12, 2014
https://doi.org/10.1371/journal.pone.0107142

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Cell cycle and cell division
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