NOX4 Mediates BMP4-Induced Upregulation of TRPC1 and 6 Protein Expressions in Distal Pulmonary Arterial Smooth Muscle Cells

Qian Jiang; Xin Fu; Lichun Tian; Yuqin Chen; Kai Yang; Xiuqing Chen; Jie Zhang; Wenju Lu; Jian Wang

doi:10.1371/journal.pone.0107135

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Open Access

Peer-reviewed

Research Article

NOX4 Mediates BMP4-Induced Upregulation of TRPC1 and 6 Protein Expressions in Distal Pulmonary Arterial Smooth Muscle Cells

Qian Jiang,

Affiliation State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
⨯
Xin Fu,

Affiliation State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
⨯
Lichun Tian,

Affiliation State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
⨯
Yuqin Chen,

Affiliation State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
⨯
Kai Yang,

Affiliations State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Xiuqing Chen,

Affiliation State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
⨯
Jie Zhang,

Affiliation State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
⨯
Wenju Lu ,

* E-mail: jwang31@jhmi.edu (JW); wlu92@yahoo.com (WL)

Affiliation State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
⨯
Jian Wang

* E-mail: jwang31@jhmi.edu (JW); wlu92@yahoo.com (WL)

Affiliations State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, The 1st Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Pulmonary, Inner Mongolia People’s Hospital, Huhhot, Inner Mongolia, China
⨯

NOX4 Mediates BMP4-Induced Upregulation of TRPC1 and 6 Protein Expressions in Distal Pulmonary Arterial Smooth Muscle Cells

Qian Jiang,
Xin Fu,
Lichun Tian,
Yuqin Chen,
Kai Yang,
Xiuqing Chen,
Jie Zhang,
Wenju Lu,
Jian Wang

Published: September 9, 2014
https://doi.org/10.1371/journal.pone.0107135

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