Quantification of the Heterogeneity of Prognostic Cellular Biomarkers in Ewing Sarcoma Using Automated Image and Random Survival Forest Analysis

• Claudia Bühnemann ,

  Contributed equally to this work with: Claudia Bühnemann, Simon Li

  Affiliation CR-UK, Tumour Growth Group, Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom

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• Simon Li ,

  Contributed equally to this work with: Claudia Bühnemann, Simon Li

  Affiliation Institute of Biomedical Engineering, Department of Engineering Science, Old Road Campus Research Building, University of Oxford, Headington, Oxford, United Kingdom

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• Haiyue Yu,

  Affiliations CR-UK, Tumour Growth Group, Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom, Institute of Biomedical Engineering, Department of Engineering Science, Old Road Campus Research Building, University of Oxford, Headington, Oxford, United Kingdom

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• Harriet Branford White,

  Affiliation CR-UK, Tumour Growth Group, Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom

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• Karl L. Schäfer,

  Affiliation Institute of Pathology, Heinrich-Heine University, Medical Faculty, Düsseldorf, Germany

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• Antonio Llombart-Bosch,

  Affiliation Pathology Department, University of Valencia, Valencia, Spain

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• Isidro Machado,

  Affiliation Pathology Department, University of Valencia, Valencia, Spain

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• Piero Picci,

  Affiliation Research, The Rizzoli Institute, Bologna, Italy

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• Pancras C. W. Hogendoorn,

  Affiliation Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands

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• Nicholas A. Athanasou,

  Affiliation Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom

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• J. Alison Noble,

  Affiliation Institute of Biomedical Engineering, Department of Engineering Science, Old Road Campus Research Building, University of Oxford, Headington, Oxford, United Kingdom

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• A. Bassim Hassan

  * E-mail: bass.hassan@path.ox.ac.uk

  Affiliation CR-UK, Tumour Growth Group, Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom

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