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Open Access

Peer-reviewed

Research Article

Silencing of the hTERT Gene by shRNA Inhibits Colon Cancer SW480 Cell Growth In Vitro and In Vivo

Ai-Qun Liu ,

Contributed equally to this work with: Ai-Qun Liu, Lian-Ying Ge, Xiao-Ling Lu

* E-mail: gelianying2008@163.com (LYG); liuaiqun_2004@163.com (AQL)

Affiliation Department of Endoscopy, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, P.R. China
⨯
Lian-Ying Ge ,

Contributed equally to this work with: Ai-Qun Liu, Lian-Ying Ge, Xiao-Ling Lu

* E-mail: gelianying2008@163.com (LYG); liuaiqun_2004@163.com (AQL)

Affiliation Department of Endoscopy, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, P.R. China
⨯
Xiao-Ling Lu ,

Contributed equally to this work with: Ai-Qun Liu, Lian-Ying Ge, Xiao-Ling Lu

Affiliation National Center for International Research of Biological Targeting Diagnosis and Therapy, Guangxi Key Laboratory of Biological Targeting Diagnosis and Therapy Research, Guangxi Medical University, Nanning, Guangxi, P.R. China
⨯
Xiao-Ling Luo,

Affiliation Science and Technology Agency, Guangxi Medical University, Nanning, Guangxi, P.R. China
⨯
Yan-Ling Cai,

Affiliation Department of Endoscopy, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, P.R. China
⨯
Xing-Qing Ye,

Affiliation Department of Pathology, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, P.R. China
⨯
Fang-Fang Geng

Affiliation Department of Endoscopy, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, P.R. China
⨯

Silencing of the hTERT Gene by shRNA Inhibits Colon Cancer SW480 Cell Growth In Vitro and In Vivo

Ai-Qun Liu,
Lian-Ying Ge,
Xiao-Ling Lu,
Xiao-Ling Luo,
Yan-Ling Cai,
Xing-Qing Ye,
Fang-Fang Geng

x

Published: September 10, 2014
https://doi.org/10.1371/journal.pone.0107019

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Transfection
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Apoptosis
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Colorectal cancer
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SW480 cells
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Cancer treatment
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Small interfering RNA
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Cancers and neoplasms
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Mouse models
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