An In Vitro Cord Formation Assay Identifies Unique Vascular Phenotypes Associated with Angiogenic Growth Factors

Beverly L. Falcon; Michelle Swearingen; Wendy H. Gough; Linda Lee; Robert Foreman; Mark Uhlik; Jeff C. Hanson; Jonathan A. Lee; Don B. McClure; Sudhakar Chintharlapalli

doi:10.1371/journal.pone.0106901

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Peer-reviewed

Research Article

An In Vitro Cord Formation Assay Identifies Unique Vascular Phenotypes Associated with Angiogenic Growth Factors

Beverly L. Falcon ,

Contributed equally to this work with: Beverly L. Falcon, Sudhakar Chintharlapalli

Affiliation Department of Cancer Angiogenesis, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Michelle Swearingen,

Affiliation Department of Cancer Angiogenesis, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Wendy H. Gough,

Affiliation Department of Quantitative Biology, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Linda Lee,

Affiliation Department of Cancer Angiogenesis, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Robert Foreman,

Affiliation Department of In Vivo Pharmacology, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Mark Uhlik,

Affiliation Department of Cancer Angiogenesis, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Jeff C. Hanson,

Affiliation Department of Informatics Capabilities, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Jonathan A. Lee,

Affiliation Department of Quantitative Biology, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Don B. McClure,

Affiliation Department of BioTDR, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯
Sudhakar Chintharlapalli

Contributed equally to this work with: Beverly L. Falcon, Sudhakar Chintharlapalli

* E-mail: chintharlapalli_sudhakar@lilly.com

Affiliation Department of Cancer Angiogenesis, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, United States of America
⨯

An In Vitro Cord Formation Assay Identifies Unique Vascular Phenotypes Associated with Angiogenic Growth Factors

Beverly L. Falcon,
Michelle Swearingen,
Wendy H. Gough,
Linda Lee,
Robert Foreman,
Mark Uhlik,
Jeff C. Hanson,
Jonathan A. Lee,
Don B. McClure,
Sudhakar Chintharlapalli

Published: September 11, 2014
https://doi.org/10.1371/journal.pone.0106901

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