Atomic Layer Deposition Coating of Carbon Nanotubes with Aluminum Oxide Alters Pro-Fibrogenic Cytokine Expression by Human Mononuclear Phagocytes In Vitro and Reduces Lung Fibrosis in Mice In Vivo

Alexia J. Taylor; Christina D. McClure; Kelly A. Shipkowski; Elizabeth A. Thompson; Salik Hussain; Stavros Garantziotis; Gregory N. Parsons; James C. Bonner

doi:10.1371/journal.pone.0106870

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Research Article

Atomic Layer Deposition Coating of Carbon Nanotubes with Aluminum Oxide Alters Pro-Fibrogenic Cytokine Expression by Human Mononuclear Phagocytes In Vitro and Reduces Lung Fibrosis in Mice In Vivo

Alexia J. Taylor,

Affiliation Environmental and Molecular Toxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Christina D. McClure,

Affiliation Department of Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Kelly A. Shipkowski,

Affiliation Environmental and Molecular Toxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Elizabeth A. Thompson,

Affiliation Environmental and Molecular Toxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
Salik Hussain,

Affiliation Clinical Research Unit, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America
⨯
Stavros Garantziotis,

Affiliation Clinical Research Unit, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America
⨯
Gregory N. Parsons,

Affiliation Department of Chemical & Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, United States of America
⨯
James C. Bonner

* E-mail: james_bonner@ncsu.edu

Affiliation Environmental and Molecular Toxicology Program, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America
⨯

Atomic Layer Deposition Coating of Carbon Nanotubes with Aluminum Oxide Alters Pro-Fibrogenic Cytokine Expression by Human Mononuclear Phagocytes In Vitro and Reduces Lung Fibrosis in Mice In Vivo

Alexia J. Taylor,
Christina D. McClure,
Kelly A. Shipkowski,
Elizabeth A. Thompson,
Salik Hussain,
Stavros Garantziotis,
Gregory N. Parsons,
James C. Bonner

Published: September 12, 2014
https://doi.org/10.1371/journal.pone.0106870

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Carbon nanotubes
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Coatings
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Fibrosis
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