Urotensin II Inhibits Doxorubicin-Induced Human Umbilical Vein Endothelial Cell Death by Modulating ATF Expression and via the ERK and Akt Pathway

Yen-Ling Chen; Yi-Ting Tsai; Chung-Yi Lee; Chien-Hsing Lee; Chung-Yi Chen; Chi-Ming Liu; Jin-Jer Chen; Shih-Hurng Loh; Chien-Sung Tsai

doi:10.1371/journal.pone.0106812

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Peer-reviewed

Research Article

Urotensin II Inhibits Doxorubicin-Induced Human Umbilical Vein Endothelial Cell Death by Modulating ATF Expression and via the ERK and Akt Pathway

Yen-Ling Chen,

Affiliation Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan, Republic of China
⨯
Yi-Ting Tsai,

Affiliations Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan, Republic of China, Division of Cardiovascular Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
⨯
Chung-Yi Lee,

Affiliation Division of Cardiovascular Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
⨯
Chien-Hsing Lee,

Affiliation Department of Nursing, Min-Hwei College of Health Care Management, Tainan, Taiwan, Republic of China
⨯
Chung-Yi Chen,

Affiliation School of Medical and Health Sciences, Fooyin University, Kaohsiung, Taiwan, Republic of China
⨯
Chi-Ming Liu,

Affiliation School of Medical and Health Sciences, Fooyin University, Kaohsiung, Taiwan, Republic of China
⨯
Jin-Jer Chen,

Affiliations Division of Cardiology, Department of Internal Medicine and Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan, Republic of China, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, Republic of China, Division of Cardiology, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan, Republic of China
⨯
Shih-Hurng Loh ,

* E-mail: sung1500@mail.ndmctsgh.edu.tw (C-ST); shloh@mail.ndmctsgh.edu.tw (S-HL)

Affiliations Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan, Republic of China, Department of Pharmacology, National Defense Medical Center, Taipei, Taiwan, Republic of China
⨯
Chien-Sung Tsai

* E-mail: sung1500@mail.ndmctsgh.edu.tw (C-ST); shloh@mail.ndmctsgh.edu.tw (S-HL)

Affiliations Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan, Republic of China, Division of Cardiovascular Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
⨯

Urotensin II Inhibits Doxorubicin-Induced Human Umbilical Vein Endothelial Cell Death by Modulating ATF Expression and via the ERK and Akt Pathway

Yen-Ling Chen,
Yi-Ting Tsai,
Chung-Yi Lee,
Chien-Hsing Lee,
Chung-Yi Chen,
Chi-Ming Liu,
Jin-Jer Chen,
Shih-Hurng Loh,
Chien-Sung Tsai

Published: September 30, 2014
https://doi.org/10.1371/journal.pone.0106812

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