Low Intensity Pulsed Ultrasound Enhanced Mesenchymal Stem Cell Recruitment through Stromal Derived Factor-1 Signaling in Fracture Healing

Fang-Yuan Wei; Kwok-Sui Leung; Gang Li; Jianghui Qin; Simon Kwoon-Ho Chow; Shuo Huang; Ming-Hui Sun; Ling Qin; Wing-Hoi Cheung

doi:10.1371/journal.pone.0106722

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Open Access

Peer-reviewed

Research Article

Low Intensity Pulsed Ultrasound Enhanced Mesenchymal Stem Cell Recruitment through Stromal Derived Factor-1 Signaling in Fracture Healing

Fang-Yuan Wei,

Affiliation Department of Orthopaedics and Traumatology, Clinical Sciences Building, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
⨯
Kwok-Sui Leung,

Affiliations Department of Orthopaedics and Traumatology, Clinical Sciences Building, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China, Translational Medicine Research & Development Center, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
⨯
Gang Li,

Affiliation Department of Orthopaedics and Traumatology, Clinical Sciences Building, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
⨯
Jianghui Qin,

Affiliation Department of Orthopaedics and Traumatology, Clinical Sciences Building, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
⨯
Simon Kwoon-Ho Chow,

Affiliation Department of Orthopaedics and Traumatology, Clinical Sciences Building, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
⨯
Shuo Huang,

Affiliation Department of Orthopaedics and Traumatology, Clinical Sciences Building, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
⨯
Ming-Hui Sun,

Affiliation Department of Orthopaedics and Traumatology, Clinical Sciences Building, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
⨯
Ling Qin,

Affiliations Department of Orthopaedics and Traumatology, Clinical Sciences Building, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China, Translational Medicine Research & Development Center, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
⨯
Wing-Hoi Cheung

* E-mail: louis@ort.cuhk.edu.hk

Affiliations Department of Orthopaedics and Traumatology, Clinical Sciences Building, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China, Translational Medicine Research & Development Center, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
⨯

Low Intensity Pulsed Ultrasound Enhanced Mesenchymal Stem Cell Recruitment through Stromal Derived Factor-1 Signaling in Fracture Healing

Fang-Yuan Wei,
Kwok-Sui Leung,
Gang Li,
Jianghui Qin,
Simon Kwoon-Ho Chow,
Shuo Huang,
Ming-Hui Sun,
Ling Qin,
Wing-Hoi Cheung

Published: September 2, 2014
https://doi.org/10.1371/journal.pone.0106722

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Bone fracture
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Mesenchymal stem cells
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Tissue repair
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Cell migration
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Wound healing
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Bone and joint mechanics
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