Functional Changes in Pulmonary Arterial Endothelial Cells Associated with BMPR2 Mutations

Hu Wang; Ruirui Ji; Jie Meng; Qiqiong Cui; Wenxin Zou; Lei Li; Guoliang Wang; Li Sun; Zhaohui Li; Lei Huo; Yuxin Fan; Daniel J. Penny

doi:10.1371/journal.pone.0106703

Loading metrics

Open Access

Peer-reviewed

Research Article

Functional Changes in Pulmonary Arterial Endothelial Cells Associated with BMPR2 Mutations

Hu Wang ,

Contributed equally to this work with: Hu Wang, Ruirui Ji

Affiliation Section of Cardiology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Ruirui Ji ,

Contributed equally to this work with: Hu Wang, Ruirui Ji

Affiliation Section of Cardiology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Jie Meng,

Affiliation Section of Cardiology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Qiqiong Cui,

Affiliation Cardiovascular Clinical Research Core, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Wenxin Zou,

Affiliation Section of Cardiology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Lei Li,

Affiliation Section of Cardiology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Guoliang Wang,

Affiliation Section of Cardiology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Li Sun,

Affiliation Department of Pathology, The University of Texas, MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Zhaohui Li,

Affiliation Section of Cardiology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Lei Huo,

Affiliation Department of Pathology, The University of Texas, MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Yuxin Fan ,

* E-mail: yuxinf@bcm.edu

Affiliation Section of Cardiology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Daniel J. Penny

Affiliation Section of Cardiology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States of America
⨯

Functional Changes in Pulmonary Arterial Endothelial Cells Associated with BMPR2 Mutations

Hu Wang,
Ruirui Ji,
Jie Meng,
Qiqiong Cui,
Wenxin Zou,
Lei Li,
Guoliang Wang,
Li Sun,
Zhaohui Li,
Lei Huo

Published: September 4, 2014
https://doi.org/10.1371/journal.pone.0106703

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Endothelial cells
Is the Subject Area "Endothelial cells" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Pulmonary arteries
Is the Subject Area "Pulmonary arteries" applicable to this article?

Thanks for your feedback.
Cell proliferation
Is the Subject Area "Cell proliferation" applicable to this article?

Thanks for your feedback.
Nitric oxide
Is the Subject Area "Nitric oxide" applicable to this article?

Thanks for your feedback.
Nonsense mutation
Is the Subject Area "Nonsense mutation" applicable to this article?

Thanks for your feedback.
Subcellular localization
Is the Subject Area "Subcellular localization" applicable to this article?

Thanks for your feedback.